Trial Watch-Oncolytic viruses and cancer therapy

Oncolytic virotherapy relies on the administration of non-pathogenic viral strains that selectively infect and kill malignant cells while favoring the elicitation of a therapeutically relevant tumor-targeting immune response. During the past few years, great efforts have been dedicated to the develo...

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Published inOncoimmunology Vol. 5; no. 2; p. e1117740
Main Authors Pol, Jonathan, Buqué, Aitziber, Aranda, Fernando, Bloy, Norma, Cremer, Isabelle, Eggermont, Alexander, Erbs, Philippe, Fucikova, Jitka, Galon, Jérôme, Limacher, Jean-Marc, Preville, Xavier, Sautès-Fridman, Catherine, Spisek, Radek, Zitvogel, Laurence, Kroemer, Guido, Galluzzi, Lorenzo
Format Journal Article
LanguageEnglish
Published United States Taylor & Francis 01.02.2016
Subjects
Cavatak
GM-CSF
JX-594
ONCOS-102
Reolysin
Review
talimogene laherparepvec
Cavatak
JX-594
GM-CSF
Reolysin
talimogene laherparepvec
ONCOS-102
Online AccessGet full text
ISSN2162-402X
2162-4011
2162-402X
DOI10.1080/2162402X.2015.1117740

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Abstract Oncolytic virotherapy relies on the administration of non-pathogenic viral strains that selectively infect and kill malignant cells while favoring the elicitation of a therapeutically relevant tumor-targeting immune response. During the past few years, great efforts have been dedicated to the development of oncolytic viruses with improved specificity and potency. Such an intense wave of investigation has culminated this year in the regulatory approval by the US Food and Drug Administration (FDA) of a genetically engineered oncolytic viral strain for use in melanoma patients. Here, we summarize recent preclinical and clinical advances in oncolytic virotherapy.
AbstractList Oncolytic virotherapy relies on the administration of non-pathogenic viral strains that selectively infect and kill malignant cells while favoring the elicitation of a therapeutically relevant tumor-targeting immune response. During the past few years, great efforts have been dedicated to the development of oncolytic viruses with improved specificity and potency. Such an intense wave of investigation has culminated this year in the regulatory approval by the US Food and Drug Administration (FDA) of a genetically engineered oncolytic viral strain for use in melanoma patients. Here, we summarize recent preclinical and clinical advances in oncolytic virotherapy.
Author Spisek, Radek
Eggermont, Alexander
Limacher, Jean-Marc
Buqué, Aitziber
Sautès-Fridman, Catherine
Bloy, Norma
Zitvogel, Laurence
Galluzzi, Lorenzo
Cremer, Isabelle
Erbs, Philippe
Galon, Jérôme
Fucikova, Jitka
Pol, Jonathan
Aranda, Fernando
Preville, Xavier
Kroemer, Guido
Author_xml – sequence: 1
  givenname: Jonathan
  surname: Pol
  fullname: Pol, Jonathan
  organization: Gustave Roussy Cancer Campus
– sequence: 2
  givenname: Aitziber
  surname: Buqué
  fullname: Buqué, Aitziber
  organization: Gustave Roussy Cancer Campus
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  givenname: Fernando
  surname: Aranda
  fullname: Aranda, Fernando
  organization: Group of Immune receptors of the Innate and Adaptive System, Institut d'Investigacions Biomédiques August Pi i Sunyer (IDIBAPS)
– sequence: 4
  givenname: Norma
  surname: Bloy
  fullname: Bloy, Norma
  organization: Gustave Roussy Cancer Campus
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  givenname: Isabelle
  surname: Cremer
  fullname: Cremer, Isabelle
  organization: Equipe 13, Center de Recherche des Cordeliers
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  givenname: Alexander
  surname: Eggermont
  fullname: Eggermont, Alexander
  organization: Gustave Roussy Cancer Campus
– sequence: 7
  givenname: Philippe
  surname: Erbs
  fullname: Erbs, Philippe
  organization: Transgene S.A
– sequence: 8
  givenname: Jitka
  surname: Fucikova
  fullname: Fucikova, Jitka
  organization: Dept. of Immunology, 2nd Faculty of Medicine and University Hospital Motol, Charles University
– sequence: 9
  givenname: Jérôme
  surname: Galon
  fullname: Galon, Jérôme
  organization: Laboratory of Integrative Cancer Immunology, Centre de Recherche des Cordeliers
– sequence: 10
  givenname: Jean-Marc
  surname: Limacher
  fullname: Limacher, Jean-Marc
  organization: Transgene S.A
– sequence: 11
  givenname: Xavier
  surname: Preville
  fullname: Preville, Xavier
  organization: Transgene S.A
– sequence: 12
  givenname: Catherine
  surname: Sautès-Fridman
  fullname: Sautès-Fridman, Catherine
  organization: Equipe 13, Center de Recherche des Cordeliers
– sequence: 13
  givenname: Radek
  surname: Spisek
  fullname: Spisek, Radek
  organization: Dept. of Immunology, 2nd Faculty of Medicine and University Hospital Motol, Charles University
– sequence: 14
  givenname: Laurence
  surname: Zitvogel
  fullname: Zitvogel, Laurence
  organization: INSERM, U1015, CICBT507
– sequence: 15
  givenname: Guido
  surname: Kroemer
  fullname: Kroemer, Guido
  email: deadoc@vodafone.it, kroemer@orange.fr
  organization: Department of Women's and Children's Health, Karolinska University Hospital
– sequence: 16
  givenname: Lorenzo
  surname: Galluzzi
  fullname: Galluzzi, Lorenzo
  email: deadoc@vodafone.it, kroemer@orange.fr
  organization: Gustave Roussy Cancer Campus
BackLink https://www.ncbi.nlm.nih.gov/pubmed/27057469$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1158/0008-5472.CAN-11-2975
10.4161/21624011.2014.955697
10.1186/1743-422X-10-241
10.1097/CCO.0000000000000004
10.4161/onci.25595
10.4161/onci.27255
10.1016/j.ejca.2005.07.006
10.4161/21624011.2014.954919
10.1038/nmeth.1346
10.1016/j.jhep.2013.07.010
10.1146/annurev-immunol-032712-100008
10.1056/NEJM200301163480314
10.1200/JCO.2014.58.3377
10.18632/oncotarget.2151
10.1371/journal.pone.0081768
10.1158/1078-0432.CCR-08-0524
10.1016/B978-0-12-398342-8.00008-2
10.18632/oncotarget.1430
10.1038/mt.2011.29
10.18632/oncotarget.1921
10.4161/21624011.2014.955691
10.18632/oncotarget.1839
10.1186/1479-5876-11-20
10.1038/cddis.2012.1
10.1158/1078-0432.CCR-14-1404
10.18632/oncotarget.2901
10.1038/bcj.2013.23
10.4161/onci.24117
10.1038/gt.2008.82
10.4161/21624011.2014.963413
10.1158/0008-5472.CAN-11-3001
10.1038/mt.2015.109
10.4161/onci.20639
10.1089/hum.2010.020
10.1038/mt.2014.194
10.18632/oncotarget.2998
10.1002/ijc.27770
10.3892/or_00000864
10.1038/ncomms7410
10.18632/oncotarget.1596
10.1093/jnci/93.13.998
10.1016/j.immuni.2013.06.014
10.2174/138920112800958760
10.4161/21624011.2014.968434
10.4161/onci.27218
10.1128/JVI.03508-13
10.1371/journal.pone.0073964
10.4161/onci.27622
10.1089/hum.2014.072
10.3748/wjg.v19.i31.5138
10.1038/cgt.2013.51
10.3892/or.2012.2217
10.1016/j.cytogfr.2010.02.005
10.1155/2013/387362
10.4161/21624011.2014.947872
10.1002/pbc.25464
10.1038/mt.2014.243
10.1371/journal.ppat.1003155
10.1038/nrd4643
10.1358/dot.2015.51.9.2383044
10.1038/mt.2014.21
10.4161/onci.23510
10.1002/hed.23309
10.1038/nrclinonc.2015.106
10.1089/hum.2012.205
10.1158/0008-5472.CAN-12-3056
10.1038/nbt.2287
10.3389/fonc.2014.00188
10.1002/pbc.25269
10.1038/sj.gt.3301389
10.4161/onci.22197
10.4161/onci.29179
10.1126/science.282.5392.1332
10.1016/j.clim.2013.05.019
10.1038/sj.gt.3302770
10.1038/sj.onc.1206464
10.1182/blood-2003-07-2233
10.1016/j.chom.2014.01.002
10.1002/cncr.21203
10.4161/21624011.2014.955331
10.4161/onci.25083
10.1038/gt.2013.28
10.1038/sj.cgt.7700160
10.1038/nri3806
10.4161/onci.24612
10.1038/sj.cgt.7700962
10.1038/mt.2009.154
10.1158/0008-5472.CAN-12-0658
10.4049/jimmunol.1400201
10.1038/mt.2008.130
10.1007/s13277-013-0701-7
10.1038/nrd3626
10.1038/mt.2013.249
10.4161/onci.26441
10.4161/onci.24212
10.1038/nm.1776
10.1089/hum.2011.146
10.1128/JVI.00204-09
10.1186/1479-5876-11-185
10.4161/cbt.26043
10.1016/j.juro.2012.07.097
10.1002/pbc.22535
10.1038/mt.2010.26
10.1016/j.ijrobp.2014.02.034
10.4161/onci.23991
10.1158/0008-5472.CAN-14-0697
10.1593/neo.121272
10.2217/nnm.12.50
10.4161/21624011.2014.953407
10.1038/nm.3089
10.18632/oncotarget.2579
10.4161/cbt.5.4.2542
10.1002/ijc.28696
10.1158/1078-0432.CCR-04-0081
10.4161/onci.20684
10.4049/jimmunol.1402132
10.1089/hum.2012.132
10.4161/onci.28344
10.1016/S0531-5565(02)00011-6
10.1038/nrc3770
10.1158/0008-5472.CAN-04-1335
10.1158/0008-5472.CAN-12-1597
10.4161/21624011.2014.967147
10.1177/0141076813494196
10.1038/sj.cgt.7700969
10.1038/cgt.2011.81
10.18632/oncotarget.1671
10.4161/onci.27878
10.1158/0008-5472.CAN-10-0155
10.1038/sj.gt.3302759
10.1038/mt.2010.98
10.4161/21624011.2014.958937
10.1158/1078-0432.CCR-14-0553
10.1158/1078-0432.CCR-10-2008
10.4161/onci.27562
10.1186/2051-1426-2-1
10.1371/journal.pone.0071932
10.1593/neo.13158
10.1002/ijc.29258
10.1016/j.ygyno.2013.05.004
10.1126/science.1088547
10.1038/nm.1754
10.1038/mt.2014.22
10.1038/nri3787
10.1371/journal.ppat.1000018
10.1128/JVI.74.10.4765-4775.2000
10.1038/cgt.2011.14
10.4161/onci.19369
10.1038/mt.2014.218
10.4161/onci.24238
10.1016/j.mayocp.2014.04.003
10.1016/j.ymthe.2003.07.006
10.1128/JVI.02511-10
10.1089/hum.1996.7.9-1095
10.1038/mt.2014.160
10.1186/1477-3155-4-2
10.1016/j.ymthe.2005.10.005
10.1038/gt.2013.40
10.1158/1078-0432.CCR-12-2546
10.1016/j.jviromet.2008.09.020
10.4161/onci.23139
10.1073/pnas.040557897
10.4161/onci.28518
10.1158/0008-5472.CAN-07-5312
10.1128/JVI.02984-12
10.4161/onci.23658
10.4161/onci.24850
10.4161/2162402X.2014.989771
10.1158/1078-0432.CCR-14-1770
10.1158/0008-5472.CAN-13-3472
10.1016/j.ccell.2015.06.009
10.4161/onci.25995
10.1038/leu.2015.88
10.1038/77558
10.1007/s00109-012-0985-x
10.1158/0008-5472.CAN-12-2221
10.1128/JVI.01788-09
10.1186/1479-5876-10-167
10.1038/nri3845
10.1038/gt.2009.14
10.1002/ijc.26216
10.1016/j.jhep.2013.03.033
10.1038/mt.2012.83
10.1038/sj.mt.6300400
10.1158/1538-7445.AM2015-CT205
10.1038/nm.3708
10.1080/2162402X.2015.1008814
10.4161/onci.29030
10.1016/j.canlet.2012.09.003
10.1007/s11033-013-2638-8
10.1016/S1470-2045(08)70107-4
10.18632/oncotarget.1630
10.1038/sj.gt.3302387
10.1371/journal.pone.0067512
10.18632/oncotarget.2193
10.4161/onci.27048
10.4161/onci.27845
10.2174/156800911793743673
10.1038/nm.3848
10.3892/ijo.26.6.1471
10.1016/j.canlet.2007.02.002
10.4161/onci.27058
10.4161/onci.22244
10.1182/blood.V97.12.3746
10.1371/journal.pone.0097495
10.3892/mmr.2013.1680
10.1096/fasebj.13.11.1325
10.1182/blood-2013-09-528851
10.1158/1538-7445.AM2015-CT123
10.1371/journal.pone.0054506
10.1128/JVI.02394-12
10.1007/978-1-4939-2727-2_19
10.1200/JCO.2001.19.2.289
10.1371/journal.pone.0036506
10.1038/mt.2013.51
10.4161/onci.25238
10.1038/onc.2011.384
10.1158/1078-0432.CCR-14-200
10.4161/onci.28694
10.1158/1078-0432.CCR-05-1059
10.1002/ijc.29536
10.18632/oncotarget.1018
10.2217/imt.15.35
10.1146/annurev.immunol.20.103001.114744
10.1186/1756-9966-28-81
10.1093/neuonc/nor199
10.4161/onci.27297
10.1016/S1535-6108(03)00241-1
10.18632/oncotarget.2119
10.1038/mt.2015.143
10.1038/cgt.2012.75
10.1038/gt.2013.73
10.1128/JVI.02618-05
10.1038/mt.2012.211
10.1371/journal.pone.0057340
10.1038/onc.2014.331
10.2174/1874467210801010013
10.1128/JVI.00528-06
10.1038/mt.2012.265
10.2217/imt.13.65
10.4161/onci.26442
10.1158/1078-0432.CCR-08-1360
10.1016/j.jconrel.2013.03.030
10.4161/onci.22789
10.4161/21624011.2014.954929
10.3389/fonc.2014.00155
10.4161/onci.28248
10.1007/s11864-014-0326-0
10.1002/cncr.11353
10.4161/onci.26013
10.1002/ijc.27918
10.1007/s00262-012-1279-4
10.4161/onci.23033
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JX-594
GM-CSF
Reolysin
talimogene laherparepvec
ONCOS-102
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References cit0077
cit0198
cit0078
cit0075
cit0196
cit0076
cit0197
cit0073
cit0194
cit0074
cit0195
cit0071
cit0192
cit0072
cit0193
cit0079
cit0066
cit0067
cit0188
cit0064
cit0185
cit0065
Kaufman H (cit0162) 2015; 33
cit0186
cit0062
cit0183
cit0063
cit0184
cit0060
cit0181
cit0061
cit0180
cit0068
cit0189
cit0099
cit0097
cit0098
cit0095
cit0096
cit0093
cit0094
cit0091
cit0092
cit0090
Kasuya H (cit0200) 2014; 61
Wang W (cit0054) 2014
cit0088
cit0089
cit0086
cit0087
cit0084
cit0085
cit0082
cit0083
cit0080
cit0081
Mell LK (cit0190) 2015; 33
Andtbacka RHI (cit0175) 2015; 33
cit0033
cit0154
cit0034
cit0155
cit0031
cit0152
cit0032
cit0153
Wildner O (cit0069) 1999; 59
cit0150
cit0271
cit0030
cit0151
cit0270
cit0039
cit0037
cit0158
cit0038
cit0159
cit0035
cit0156
cit0036
cit0157
cit0022
cit0143
cit0264
cit0023
cit0144
cit0265
cit0020
cit0141
cit0262
cit0263
cit0140
cit0261
cit0028
cit0149
cit0029
cit0026
cit0147
cit0027
cit0148
cit0269
cit0024
cit0145
cit0266
cit0025
cit0146
cit0055
cit0176
cit0056
cit0177
cit0053
cit0051
cit0172
cit0052
cit0173
cit0170
cit0050
cit0171
Pesonen SA (cit0182) 2015; 33
McNeish IA (cit0267) 2015; 33
Kimata H (cit0199) 2003; 50
cit0059
cit0057
cit0178
cit0058
cit0179
cit0044
cit0045
cit0166
cit0042
cit0163
cit0043
cit0164
cit0040
cit0161
cit0041
cit0160
cit0048
cit0169
cit0046
cit0167
cit0047
cit0168
cit0110
cit0231
cit0111
cit0232
cit0230
Tseng JC (cit0070) 2006; 47
Ferris RL (cit0268) 2014; 32
cit0118
Andtbacka RH (cit0174) 2015; 75
cit0239
cit0119
cit0116
cit0237
cit0117
cit0238
cit0114
cit0235
cit0115
cit0236
cit0112
cit0233
cit0113
cit0234
cit0220
cit0100
cit0221
cit0109
cit0228
cit0108
cit0229
cit0105
cit0226
cit0106
cit0227
cit0103
cit0224
cit0104
cit0225
cit0101
cit0222
cit0102
cit0223
cit0011
cit0132
Puzanov I (cit0165) 2015; 33
cit0253
cit0012
cit0133
cit0254
cit0130
cit0251
cit0010
cit0131
cit0252
cit0250
cit0019
cit0017
cit0138
cit0259
cit0018
cit0139
cit0015
cit0136
cit0257
cit0016
Peng KW (cit0021) 2002; 62
cit0137
cit0258
cit0013
cit0134
cit0255
cit0014
cit0135
cit0256
cit0121
cit0242
cit0001
cit0122
cit0243
cit0240
cit0120
cit0241
cit0008
cit0129
cit0009
cit0006
cit0127
cit0248
cit0007
cit0128
cit0249
cit0004
cit0125
cit0246
cit0005
cit0126
cit0247
cit0002
cit0123
cit0244
cit0003
cit0124
cit0245
Andtbacka RHI (cit0260) 2015; 33
Roth JC (cit0107) 2014
Kooby DA (cit0191) 1999; 13
Cuevas Y (cit0049) 2003; 63
cit0210
Nemunaitis J (cit0142) 2001; 19
Krug LM (cit0187) 2015; 33
cit0219
cit0217
cit0218
cit0215
cit0216
cit0213
cit0214
cit0211
cit0212
cit0208
cit0209
cit0206
cit0207
cit0204
cit0205
cit0202
cit0203
cit0201
References_xml – ident: cit0091
  doi: 10.1158/0008-5472.CAN-11-2975
– ident: cit0255
  doi: 10.4161/21624011.2014.955697
– ident: cit0041
  doi: 10.1186/1743-422X-10-241
– ident: cit0003
  doi: 10.1097/CCO.0000000000000004
– ident: cit0196
  doi: 10.4161/onci.25595
– ident: cit0097
  doi: 10.4161/onci.27255
– ident: cit0139
  doi: 10.1016/j.ejca.2005.07.006
– ident: cit0257
  doi: 10.4161/21624011.2014.954919
– ident: cit0068
  doi: 10.1038/nmeth.1346
– ident: cit0137
  doi: 10.1016/j.jhep.2013.07.010
– ident: cit0218
  doi: 10.1146/annurev-immunol-032712-100008
– ident: cit0144
  doi: 10.1056/NEJM200301163480314
– ident: cit0161
  doi: 10.1200/JCO.2014.58.3377
– ident: cit0056
  doi: 10.18632/oncotarget.2151
– ident: cit0113
  doi: 10.1371/journal.pone.0081768
– ident: cit0166
  doi: 10.1158/1078-0432.CCR-08-0524
– volume: 47
  start-page: 1136
  year: 2006
  ident: cit0070
  publication-title: J Nucl Med
– ident: cit0153
  doi: 10.1016/B978-0-12-398342-8.00008-2
– ident: cit0057
  doi: 10.18632/oncotarget.1430
– ident: cit0102
  doi: 10.1038/mt.2011.29
– ident: cit0065
  doi: 10.18632/oncotarget.1921
– ident: cit0150
  doi: 10.4161/21624011.2014.955691
– ident: cit0046
  doi: 10.18632/oncotarget.1839
– ident: cit0136
  doi: 10.1186/1479-5876-11-20
– ident: cit0264
  doi: 10.1038/cddis.2012.1
– ident: cit0168
  doi: 10.1158/1078-0432.CCR-14-1404
– ident: cit0181
  doi: 10.18632/oncotarget.2901
– ident: cit0017
  doi: 10.1038/bcj.2013.23
– volume: 59
  start-page: 410
  year: 1999
  ident: cit0069
  publication-title: Cancer Res
– ident: cit0232
  doi: 10.4161/onci.24117
– ident: cit0071
  doi: 10.1038/gt.2008.82
– ident: cit0261
  doi: 10.4161/21624011.2014.963413
– ident: cit0092
  doi: 10.1158/0008-5472.CAN-11-3001
– ident: cit0184
  doi: 10.1038/mt.2015.109
– ident: cit0100
  doi: 10.4161/onci.20639
– ident: cit0143
  doi: 10.1089/hum.2010.020
– ident: cit0207
  doi: 10.1038/mt.2014.194
– ident: cit0149
  doi: 10.18632/oncotarget.2998
– ident: cit0051
  doi: 10.1002/ijc.27770
– ident: cit0081
  doi: 10.3892/or_00000864
– ident: cit0214
  doi: 10.1038/ncomms7410
– ident: cit0221
  doi: 10.18632/oncotarget.1596
– ident: cit0007
  doi: 10.1093/jnci/93.13.998
– ident: cit0146
  doi: 10.1016/j.immuni.2013.06.014
– ident: cit0154
  doi: 10.2174/138920112800958760
– ident: cit0238
  doi: 10.4161/21624011.2014.968434
– ident: cit0006
  doi: 10.4161/onci.27218
– ident: cit0236
  doi: 10.1128/JVI.03508-13
– ident: cit0040
  doi: 10.1371/journal.pone.0073964
– ident: cit0271
  doi: 10.4161/onci.27622
– ident: cit0230
  doi: 10.1089/hum.2014.072
– ident: cit0125
  doi: 10.3748/wjg.v19.i31.5138
– ident: cit0249
  doi: 10.1038/cgt.2013.51
– ident: cit0066
  doi: 10.3892/or.2012.2217
– ident: cit0045
  doi: 10.1016/j.cytogfr.2010.02.005
– ident: cit0011
  doi: 10.1155/2013/387362
– ident: cit0019
  doi: 10.4161/21624011.2014.947872
– ident: cit0171
  doi: 10.1002/pbc.25464
– ident: cit0185
  doi: 10.1038/mt.2014.243
– ident: cit0035
  doi: 10.1371/journal.ppat.1003155
– ident: cit0156
  doi: 10.1038/nrd4643
– ident: cit0159
  doi: 10.1358/dot.2015.51.9.2383044
– ident: cit0167
  doi: 10.1038/mt.2014.21
– ident: cit0222
  doi: 10.4161/onci.23510
– ident: cit0052
  doi: 10.1002/hed.23309
– ident: cit0157
  doi: 10.1038/nrclinonc.2015.106
– ident: cit0124
  doi: 10.1089/hum.2012.205
– ident: cit0132
  doi: 10.1158/0008-5472.CAN-12-3056
– ident: cit0001
  doi: 10.1038/nbt.2287
– ident: cit0090
  doi: 10.3389/fonc.2014.00188
– ident: cit0194
  doi: 10.1002/pbc.25269
– ident: cit0023
  doi: 10.1038/sj.gt.3301389
– year: 2014
  ident: cit0107
  publication-title: Hum Gene Ther Clin Dev
– ident: cit0188
  doi: 10.4161/onci.22197
– ident: cit0239
  doi: 10.4161/onci.29179
– ident: cit0062
  doi: 10.1126/science.282.5392.1332
– ident: cit0099
  doi: 10.1016/j.clim.2013.05.019
– ident: cit0059
  doi: 10.1038/sj.gt.3302770
– ident: cit0050
  doi: 10.1038/sj.onc.1206464
– ident: cit0201
  doi: 10.1182/blood-2003-07-2233
– ident: cit0004
  doi: 10.1016/j.chom.2014.01.002
– ident: cit0140
  doi: 10.1002/cncr.21203
– ident: cit0208
  doi: 10.4161/21624011.2014.955331
– ident: cit0135
  doi: 10.4161/onci.25083
– ident: cit0076
  doi: 10.1038/gt.2013.28
– ident: cit0077
  doi: 10.1038/sj.cgt.7700160
– ident: cit0244
  doi: 10.1038/nri3806
– ident: cit0266
  doi: 10.4161/onci.24612
– ident: cit0072
  doi: 10.1038/sj.cgt.7700962
– ident: cit0089
  doi: 10.1038/mt.2009.154
– ident: cit0263
  doi: 10.1158/0008-5472.CAN-12-0658
– ident: cit0233
  doi: 10.4049/jimmunol.1400201
– ident: cit0038
  doi: 10.1038/mt.2008.130
– ident: cit0116
  doi: 10.1007/s13277-013-0701-7
– volume: 50
  start-page: 961
  year: 2003
  ident: cit0199
  publication-title: Hepatogastroenterology
– ident: cit0148
  doi: 10.1038/nrd3626
– ident: cit0085
  doi: 10.1038/mt.2013.249
– ident: cit0114
  doi: 10.4161/onci.26441
– ident: cit0202
  doi: 10.4161/onci.24212
– ident: cit0039
  doi: 10.1038/nm.1776
– ident: cit0031
  doi: 10.1089/hum.2011.146
– ident: cit0111
  doi: 10.1128/JVI.00204-09
– ident: cit0014
  doi: 10.1186/1479-5876-11-185
– ident: cit0079
  doi: 10.4161/cbt.26043
– ident: cit0121
  doi: 10.1016/j.juro.2012.07.097
– ident: cit0193
  doi: 10.1002/pbc.22535
– ident: cit0048
  doi: 10.1038/mt.2010.26
– ident: cit0198
  doi: 10.1016/j.ijrobp.2014.02.034
– ident: cit0262
  doi: 10.4161/onci.23991
– ident: cit0217
  doi: 10.1158/0008-5472.CAN-14-0697
– ident: cit0128
  doi: 10.1593/neo.121272
– ident: cit0131
  doi: 10.2217/nnm.12.50
– ident: cit0169
  doi: 10.4161/21624011.2014.953407
– ident: cit0122
  doi: 10.1038/nm.3089
– ident: cit0013
  doi: 10.18632/oncotarget.2579
– volume: 62
  start-page: 4656
  year: 2002
  ident: cit0021
  publication-title: Cancer Res
– ident: cit0080
  doi: 10.4161/cbt.5.4.2542
– ident: cit0177
  doi: 10.1002/ijc.28696
– ident: cit0101
  doi: 10.1158/1078-0432.CCR-04-0081
– ident: cit0108
  doi: 10.4161/onci.20684
– ident: cit0235
  doi: 10.4049/jimmunol.1402132
– ident: cit0053
  doi: 10.1089/hum.2012.132
– ident: cit0215
  doi: 10.4161/onci.28344
– ident: cit0024
  doi: 10.1016/S0531-5565(02)00011-6
– volume: 33
  start-page: 9030
  year: 2015
  ident: cit0175
  publication-title: ASCO Meeting Abstracts
– ident: cit0005
  doi: 10.1038/nrc3770
– ident: cit0204
  doi: 10.1158/0008-5472.CAN-04-1335
– ident: cit0134
  doi: 10.1158/0008-5472.CAN-12-1597
– ident: cit0147
  doi: 10.4161/21624011.2014.967147
– ident: cit0012
  doi: 10.1177/0141076813494196
– ident: cit0078
  doi: 10.1038/sj.cgt.7700969
– ident: cit0110
  doi: 10.1038/cgt.2011.81
– ident: cit0209
  doi: 10.18632/oncotarget.1671
– ident: cit0219
  doi: 10.4161/onci.27878
– ident: cit0047
  doi: 10.1158/0008-5472.CAN-10-0155
– ident: cit0094
  doi: 10.1038/sj.gt.3302759
– ident: cit0088
  doi: 10.1038/mt.2010.98
– ident: cit0178
  doi: 10.4161/21624011.2014.958937
– ident: cit0223
  doi: 10.1158/1078-0432.CCR-14-0553
– ident: cit0036
  doi: 10.1158/1078-0432.CCR-10-2008
– ident: cit0231
  doi: 10.4161/onci.27562
– ident: cit0237
  doi: 10.1186/2051-1426-2-1
– ident: cit0064
  doi: 10.1371/journal.pone.0071932
– volume: 33
  start-page: 7559
  year: 2015
  ident: cit0187
  publication-title: ASCO Meeting Abstracts
– ident: cit0105
  doi: 10.1593/neo.13158
– ident: cit0084
  doi: 10.1002/ijc.29258
– ident: cit0075
  doi: 10.1016/j.ygyno.2013.05.004
– ident: cit0145
  doi: 10.1126/science.1088547
– ident: cit0067
  doi: 10.1038/nm.1754
– volume: 32
  start-page: 6082
  year: 2014
  ident: cit0268
  publication-title: ASCO Meeting Abstracts
– ident: cit0192
  doi: 10.1038/mt.2014.22
– ident: cit0245
  doi: 10.1038/nri3787
– ident: cit0010
  doi: 10.1371/journal.ppat.1000018
– ident: cit0025
  doi: 10.1128/JVI.74.10.4765-4775.2000
– ident: cit0073
  doi: 10.1038/cgt.2011.14
– ident: cit0126
  doi: 10.4161/onci.19369
– ident: cit0180
  doi: 10.1038/mt.2014.218
– ident: cit0216
  doi: 10.4161/onci.24238
– ident: cit0203
  doi: 10.1016/j.mayocp.2014.04.003
– ident: cit0027
  doi: 10.1016/j.ymthe.2003.07.006
– year: 2014
  ident: cit0054
  publication-title: Oncotarget
– ident: cit0032
  doi: 10.1128/JVI.02511-10
– ident: cit0026
  doi: 10.1089/hum.1996.7.9-1095
– ident: cit0151
  doi: 10.1038/mt.2014.160
– ident: cit0009
  doi: 10.1186/1477-3155-4-2
– ident: cit0195
  doi: 10.1016/j.ymthe.2005.10.005
– ident: cit0106
  doi: 10.1038/gt.2013.40
– ident: cit0016
  doi: 10.1158/1078-0432.CCR-12-2546
– ident: cit0043
  doi: 10.1016/j.jviromet.2008.09.020
– ident: cit0252
  doi: 10.4161/onci.23139
– ident: cit0103
  doi: 10.1073/pnas.040557897
– ident: cit0189
  doi: 10.4161/onci.28518
– ident: cit0253
  doi: 10.1158/0008-5472.CAN-07-5312
– ident: cit0044
  doi: 10.1128/JVI.02984-12
– ident: cit0030
  doi: 10.4161/onci.23658
– ident: cit0258
  doi: 10.4161/onci.24850
– ident: cit0242
  doi: 10.4161/2162402X.2014.989771
– ident: cit0172
  doi: 10.1158/1078-0432.CCR-14-1770
– ident: cit0243
  doi: 10.1158/0008-5472.CAN-13-3472
– ident: cit0211
  doi: 10.1016/j.ccell.2015.06.009
– ident: cit0256
  doi: 10.4161/onci.25995
– ident: cit0226
  doi: 10.1038/leu.2015.88
– ident: cit0061
  doi: 10.1038/77558
– ident: cit0117
  doi: 10.1007/s00109-012-0985-x
– ident: cit0034
  doi: 10.1158/0008-5472.CAN-12-2221
– ident: cit0037
  doi: 10.1128/JVI.01788-09
– volume: 33
  start-page: 9063
  year: 2015
  ident: cit0165
  publication-title: ASCO Meeting Abstracts
– ident: cit0186
  doi: 10.1186/1479-5876-10-167
– ident: cit0210
  doi: 10.1038/nri3845
– ident: cit0098
  doi: 10.1038/gt.2009.14
– ident: cit0120
  doi: 10.1002/ijc.26216
– ident: cit0240
  doi: 10.1016/j.jhep.2013.03.033
– ident: cit0250
  doi: 10.1038/mt.2012.83
– ident: cit0254
  doi: 10.1038/sj.mt.6300400
– ident: cit0176
  doi: 10.1158/1538-7445.AM2015-CT205
– ident: cit0246
  doi: 10.1038/nm.3708
– ident: cit0164
  doi: 10.1080/2162402X.2015.1008814
– ident: cit0259
  doi: 10.4161/onci.29030
– ident: cit0074
  doi: 10.1016/j.canlet.2012.09.003
– volume: 33
  year: 2015
  ident: cit0267
  publication-title: ASCO Meeting Abstracts
– ident: cit0118
  doi: 10.1007/s11033-013-2638-8
– ident: cit0183
  doi: 10.1016/S1470-2045(08)70107-4
– ident: cit0213
  doi: 10.18632/oncotarget.1630
– ident: cit0022
  doi: 10.1038/sj.gt.3302387
– ident: cit0115
  doi: 10.1371/journal.pone.0067512
– volume: 33
  start-page: 3085
  year: 2015
  ident: cit0182
  publication-title: ASCO Meeting Abstracts
– ident: cit0220
  doi: 10.18632/oncotarget.2193
– ident: cit0225
  doi: 10.4161/onci.27048
– ident: cit0234
  doi: 10.4161/onci.27845
– volume: 75
  year: 2015
  ident: cit0174
  publication-title: Cancer Res
– ident: cit0130
  doi: 10.2174/156800911793743673
– ident: cit0229
  doi: 10.1038/nm.3848
– volume: 33
  start-page: 9074
  year: 2015
  ident: cit0162
  publication-title: ASCO Meeting Abstracts
– ident: cit0173
  doi: 10.3892/ijo.26.6.1471
– ident: cit0002
  doi: 10.1016/j.canlet.2007.02.002
– ident: cit0170
  doi: 10.4161/onci.27058
– ident: cit0227
  doi: 10.4161/onci.22244
– ident: cit0020
  doi: 10.1182/blood.V97.12.3746
– ident: cit0018
  doi: 10.1371/journal.pone.0097495
– ident: cit0119
  doi: 10.3892/mmr.2013.1680
– volume: 13
  start-page: 1325
  year: 1999
  ident: cit0191
  publication-title: FASEB J
  doi: 10.1096/fasebj.13.11.1325
– ident: cit0138
  doi: 10.1182/blood-2013-09-528851
– ident: cit0205
  doi: 10.1158/1538-7445.AM2015-CT123
– ident: cit0042
  doi: 10.1371/journal.pone.0054506
– ident: cit0055
  doi: 10.1128/JVI.02394-12
– ident: cit0265
  doi: 10.1007/978-1-4939-2727-2_19
– volume: 19
  start-page: 289
  year: 2001
  ident: cit0142
  publication-title: J Clin Oncol
  doi: 10.1200/JCO.2001.19.2.289
– ident: cit0112
  doi: 10.1371/journal.pone.0036506
– ident: cit0015
  doi: 10.1038/mt.2013.51
– ident: cit0241
  doi: 10.4161/onci.25238
– ident: cit0270
  doi: 10.1038/onc.2011.384
– ident: cit0152
  doi: 10.1158/1078-0432.CCR-14-200
– ident: cit0247
  doi: 10.4161/onci.28694
– ident: cit0248
  doi: 10.1158/1078-0432.CCR-05-1059
– volume: 33
  start-page: 6026
  year: 2015
  ident: cit0190
  publication-title: ASCO Meeting Abstracts
– ident: cit0179
  doi: 10.1002/ijc.29536
– ident: cit0083
  doi: 10.18632/oncotarget.1018
– ident: cit0160
  doi: 10.2217/imt.15.35
– ident: cit0028
  doi: 10.1146/annurev.immunol.20.103001.114744
– ident: cit0082
  doi: 10.1186/1756-9966-28-81
– ident: cit0251
  doi: 10.1093/neuonc/nor199
– ident: cit0163
  doi: 10.4161/onci.27297
– ident: cit0058
  doi: 10.1016/S1535-6108(03)00241-1
– ident: cit0212
  doi: 10.18632/oncotarget.2119
– ident: cit0029
  doi: 10.1038/mt.2015.143
– ident: cit0104
  doi: 10.1038/cgt.2012.75
– ident: cit0095
  doi: 10.1038/gt.2013.73
– ident: cit0060
  doi: 10.1128/JVI.02618-05
– ident: cit0033
  doi: 10.1038/mt.2012.211
– ident: cit0063
  doi: 10.1371/journal.pone.0057340
– ident: cit0228
  doi: 10.1038/onc.2014.331
– ident: cit0155
  doi: 10.2174/1874467210801010013
– ident: cit0008
  doi: 10.1128/JVI.00528-06
– ident: cit0086
  doi: 10.1038/mt.2012.265
– ident: cit0123
  doi: 10.2217/imt.13.65
– volume: 61
  start-page: 599
  year: 2014
  ident: cit0200
  publication-title: Hepatogastroenterology
– ident: cit0109
  doi: 10.4161/onci.26442
– ident: cit0093
  doi: 10.1158/1078-0432.CCR-08-1360
– ident: cit0129
  doi: 10.1016/j.jconrel.2013.03.030
– volume: 63
  start-page: 6877
  year: 2003
  ident: cit0049
  publication-title: Cancer Res
– ident: cit0224
  doi: 10.4161/onci.22789
– ident: cit0197
  doi: 10.4161/21624011.2014.954929
– volume: 33
  year: 2015
  ident: cit0260
  publication-title: ASCO Meeting Abstracts
– ident: cit0206
  doi: 10.3389/fonc.2014.00155
– ident: cit0096
  doi: 10.4161/onci.28248
– ident: cit0158
  doi: 10.1007/s11864-014-0326-0
– ident: cit0141
  doi: 10.1002/cncr.11353
– ident: cit0087
  doi: 10.4161/onci.26013
– ident: cit0133
  doi: 10.1002/ijc.27918
– ident: cit0127
  doi: 10.1007/s00262-012-1279-4
– ident: cit0269
  doi: 10.4161/onci.23033
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Snippet Oncolytic virotherapy relies on the administration of non-pathogenic viral strains that selectively infect and kill malignant cells while favoring the...
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SubjectTerms Cavatak
GM-CSF
JX-594
ONCOS-102
Reolysin
Review
talimogene laherparepvec
Title Trial Watch-Oncolytic viruses and cancer therapy
URI https://www.tandfonline.com/doi/abs/10.1080/2162402X.2015.1117740
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