Measuring trust in vaccination: A systematic review

Vaccine acceptance depends on public trust and confidence in the safety and efficacy of vaccines and immunization, the health system, healthcare professionals and the wider vaccine research community. This systematic review analyses the current breadth and depth of vaccine research literature that e...

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Published inHuman vaccines & immunotherapeutics Vol. 14; no. 7; pp. 1599 - 1609
Main Authors Larson, Heidi J., Clarke, Richard M., Jarrett, Caitlin, Eckersberger, Elisabeth, Levine, Zachary, Schulz, Will S., Paterson, Pauline
Format Journal Article
LanguageEnglish
Published United States Taylor & Francis 03.07.2018
Taylor & Francis Group
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Abstract Vaccine acceptance depends on public trust and confidence in the safety and efficacy of vaccines and immunization, the health system, healthcare professionals and the wider vaccine research community. This systematic review analyses the current breadth and depth of vaccine research literature that explicitly refers to the concept of trust within their stated aims or research questions. After duplicates were removed, 19,643 articles were screened by title and abstract. Of these 2,779 were screened by full text, 35 of which were included in the final analysis. These studies examined a range of trust relationships as they pertain to vaccination, including trust in healthcare professionals, the health system, the government, and friends and family members. Three studies examined generalized trust. Findings indicated that trust is often referred to implicitly (19/35), rather than explicitly examined in the context of a formal definition or discussion of the existing literature on trust in a health context. Within the quantitative research analysed, trust was commonly measured with a single-item measure (9/25). Only two studies used validated multi-item measures of trust. Three studies examined changes in trust, either following an intervention or over the course of a pandemic. The findings of this review indicate a disconnect between the current vaccine hesitancy research and the wider health-related trust literature, a dearth in research on trust in low and middle-income settings, a need for studies on how trust levels change over time and investigations on how resilience to trust-eroding information can be built into a trustworthy health system.
AbstractList Vaccine acceptance depends on public trust and confidence in the safety and efficacy of vaccines and immunization, the health system, healthcare professionals and the wider vaccine research community. This systematic review analyses the current breadth and depth of vaccine research literature that explicitly refers to the concept of trust within their stated aims or research questions. After duplicates were removed, 19,643 articles were screened by title and abstract. Of these 2,779 were screened by full text, 35 of which were included in the final analysis. These studies examined a range of trust relationships as they pertain to vaccination, including trust in healthcare professionals, the health system, the government, and friends and family members. Three studies examined generalized trust. Findings indicated that trust is often referred to implicitly (19/35), rather than explicitly examined in the context of a formal definition or discussion of the existing literature on trust in a health context. Within the quantitative research analysed, trust was commonly measured with a single-item measure (9/25). Only two studies used validated multi-item measures of trust. Three studies examined changes in trust, either following an intervention or over the course of a pandemic. The findings of this review indicate a disconnect between the current vaccine hesitancy research and the wider health-related trust literature, a dearth in research on trust in low and middle-income settings, a need for studies on how trust levels change over time and investigations on how resilience to trust-eroding information can be built into a trustworthy health system.Vaccine acceptance depends on public trust and confidence in the safety and efficacy of vaccines and immunization, the health system, healthcare professionals and the wider vaccine research community. This systematic review analyses the current breadth and depth of vaccine research literature that explicitly refers to the concept of trust within their stated aims or research questions. After duplicates were removed, 19,643 articles were screened by title and abstract. Of these 2,779 were screened by full text, 35 of which were included in the final analysis. These studies examined a range of trust relationships as they pertain to vaccination, including trust in healthcare professionals, the health system, the government, and friends and family members. Three studies examined generalized trust. Findings indicated that trust is often referred to implicitly (19/35), rather than explicitly examined in the context of a formal definition or discussion of the existing literature on trust in a health context. Within the quantitative research analysed, trust was commonly measured with a single-item measure (9/25). Only two studies used validated multi-item measures of trust. Three studies examined changes in trust, either following an intervention or over the course of a pandemic. The findings of this review indicate a disconnect between the current vaccine hesitancy research and the wider health-related trust literature, a dearth in research on trust in low and middle-income settings, a need for studies on how trust levels change over time and investigations on how resilience to trust-eroding information can be built into a trustworthy health system.
Vaccine acceptance depends on public trust and confidence in the safety and efficacy of vaccines and immunization, the health system, healthcare professionals and the wider vaccine research community. This systematic review analyses the current breadth and depth of vaccine research literature that explicitly refers to the concept of trust within their stated aims or research questions. After duplicates were removed, 19,643 articles were screened by title and abstract. Of these 2,779 were screened by full text, 35 of which were included in the final analysis. These studies examined a range of trust relationships as they pertain to vaccination, including trust in healthcare professionals, the health system, the government, and friends and family members. Three studies examined generalized trust. Findings indicated that trust is often referred to implicitly (19/35), rather than explicitly examined in the context of a formal definition or discussion of the existing literature on trust in a health context. Within the quantitative research analysed, trust was commonly measured with a single-item measure (9/25). Only two studies used validated multi-item measures of trust. Three studies examined changes in trust, either following an intervention or over the course of a pandemic. The findings of this review indicate a disconnect between the current vaccine hesitancy research and the wider health-related trust literature, a dearth in research on trust in low and middle-income settings, a need for studies on how trust levels change over time and investigations on how resilience to trust-eroding information can be built into a trustworthy health system.
Author Jarrett, Caitlin
Levine, Zachary
Eckersberger, Elisabeth
Clarke, Richard M.
Paterson, Pauline
Schulz, Will S.
Larson, Heidi J.
Author_xml – sequence: 1
  givenname: Heidi J.
  surname: Larson
  fullname: Larson, Heidi J.
  email: heidi.larson@lshtm.ac.uk
  organization: Department of Global Health, University of Washington
– sequence: 2
  givenname: Richard M.
  surname: Clarke
  fullname: Clarke, Richard M.
  organization: Department of Infectious Disease Epidemiology, The Vaccine Confidence Project, London School of Hygiene & Tropical Medicine
– sequence: 3
  givenname: Caitlin
  surname: Jarrett
  fullname: Jarrett, Caitlin
  organization: Swiss Tropical and Public Health Institute
– sequence: 4
  givenname: Elisabeth
  surname: Eckersberger
  fullname: Eckersberger, Elisabeth
  organization: Ipas
– sequence: 5
  givenname: Zachary
  surname: Levine
  fullname: Levine, Zachary
  organization: Department of Infectious Disease Epidemiology, The Vaccine Confidence Project, London School of Hygiene & Tropical Medicine
– sequence: 6
  givenname: Will S.
  surname: Schulz
  fullname: Schulz, Will S.
  organization: Department of Infectious Disease Epidemiology, The Vaccine Confidence Project, London School of Hygiene & Tropical Medicine
– sequence: 7
  givenname: Pauline
  surname: Paterson
  fullname: Paterson, Pauline
  organization: Department of Infectious Disease Epidemiology, The Vaccine Confidence Project, London School of Hygiene & Tropical Medicine
BackLink https://www.ncbi.nlm.nih.gov/pubmed/29617183$$D View this record in MEDLINE/PubMed
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SubjectTerms Communication
confidence
Female
Health Knowledge, Attitudes, Practice
Health Personnel
Humans
immunization/immunisation
Male
Patient Acceptance of Health Care
Pregnancy
Reviews
Trust
vaccination
Vaccination - psychology
Vaccination Refusal - psychology
Vaccination Refusal - statistics & numerical data
vaccines
Vaccines - administration & dosage
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Title Measuring trust in vaccination: A systematic review
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