Response characteristics of subthalamic neurons to the stimulation of the sensorimotor cortex in the rat

• Published in: Brain research Vol. 609; no. 1; pp. 185 - 192
• Main Authors: Fujimoto, K., Kita, H.
• Format: Journal Article
• Language: English
• Published: London Elsevier B.V 23.04.1993; Amsterdam Elsevier; New York, NY
• Subjects: Animals; Biological and medical sciences; Brain Stem - cytology; Brain Stem - physiology; Corpus Callosum - cytology; Corpus Callosum - physiology; Corpus Striatum - cytology; Corpus Striatum - physiology; Electric Stimulation; Evoked Potentials - drug effects; Evoked Potentials - physiology; Experimental brain lesion; Fundamental and applied biological sciences. Psychology; Globus Pallidus - cytology; Globus Pallidus - physiology; Ibotenic Acid - pharmacology; Male; Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration; Motor Cortex - physiology; Neurons - physiology; Quinolinic Acid - pharmacology; Rats; Rats, Sprague-Dawley; Sensorimotor cortex; Somatosensory Cortex - physiology; Subthalamic nucleus; Thalamic Nuclei - physiology; Unit and intracellular recording; Vertebrates: nervous system and sense organs; Unit and intracellular recording; Experimental brain lesion; Sensorimotor cortex; Subthalamic nucleus; Motor pathway; Rat; Rodentia; Central nervous system; Discharge pattern; Electrophysiology; Somatosensory cortex; Vertebrata; Sensorimotor coordination; Mammalia; Synaptic transmission; Afferent projection; Postsynaptic potential; Brain (vertebrata)

Responses of the subthalamic nucleus (STH) neurons to the stimulation of the sensorimotor cortex (Cx) were recorded in intact rats and in those which received lesions in the pallidum, the neostriatum, the brainstem, or the corpus callosum. Most of the STH units (78%) exhibited two excitatory peaks w...