Fecal microbiome analysis as a diagnostic test for diverticulitis

• Published in: European journal of clinical microbiology & infectious diseases Vol. 33; no. 11; pp. 1927 - 1936
• Main Authors: Daniels, L., Budding, A. E., de Korte, N., Eck, A., Bogaards, J. A., Stockmann, H. B., Consten, E. C., Savelkoul, P. H., Boermeester, M. A.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.11.2014; Springer; Springer Nature B.V
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Bacteriological Techniques - methods; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Biostatistics; Computed tomography; Diagnostic tests; Diagnostic Tests, Routine - methods; Discriminant analysis; Diverticulitis; Diverticulitis - diagnosis; Enterobacteriaceae; Feces; Feces - microbiology; Firmicutes; Gastroenterology. Liver. Pancreas. Abdomen; High-Throughput Screening Assays; Hospitals; Humans; Infectious diseases; Internal Medicine; Male; Medical Microbiology; Medical sciences; Metabolism; Microbiota; Middle Aged; Molecular Diagnostic Techniques - methods; Other diseases. Semiology; Polymerase Chain Reaction; Prediction models; Proteobacteria; Randomized Controlled Trials as Topic; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; Surgery; Tomography; Young Adult; Netherlands; Partial Little Square Discriminant Analysis; Diverticular Disease; Rifaximin; Intestinal Microbiota; Diverticulitis; Infection; Digestive diseases; Intestinal disease; Diagnosis; Microbiology

Disease-specific variations in intestinal microbiome composition have been found for a number of intestinal disorders, but little is known about diverticulitis. The purpose of this study was to compare the fecal microbiota of diverticulitis patients with control subjects from a general gastroenterol...