Transmembrane domains of type III-secreted proteins affect bacterial-host interactions in enteropathogenic E. coli

• Published in: Virulence Vol. 12; no. 1; pp. 902 - 917
• Main Authors: Gershberg, Jenia, Braverman, Dor, Sal-Man, Neta
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.12.2021; Taylor & Francis Group
• Subjects: bacterial virulence; epec; espb; espd; pore complex; Research Paper; SctB; scte; transmembrane domain; type III secretion system; pore complex; bacterial virulence; scte; transmembrane domain; epec; type III secretion system; SctB; espd; espb

Many bacterial pathogens utilize a specialized secretion system, termed type III secretion system (T3SS), to translocate effector proteins into host cells and establish bacterial infection. The T3SS is anchored within the bacterial membranes and contains a long needle/filament that extends toward th...