Effect of probiotics, Bifidobacterium bifidum G9-1, on gastrointestinal symptoms in patients with type 2 diabetes mellitus: study protocol for open-label, single-arm, exploratory research trial (Big STAR study) - Hashimoto, Yoshitaka; Nakajima, Hanako; Hata, Shinnosuke; Miyoshi, Tomoki; Hosomi, Yukako; Majima, Saori; Nakanishi, Naoko; Senmaru, Takafumi; Osaka, Takafumi; Okada, Hiroshi; Ushigome, Emi; Hamaguchi, Masahide; et al. (Journal of Clinical Biochemistry and Nutrition, 2020)
Keywords: Animal models; Antidiabetics; Bifidobacterium bifidum; biguanides; Biomarkers; Body mass index; Body size; Constipation; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Diarrhea; gastrointestinal complications; Gastrointestinal symptoms; gut microbiota; Intestinal microflora; Metformin; Microbiota; Probiotics; Protocol; type 2 diabetes