A causal relationship between childhood obesity and risk of osteoarthritis: results from a two-sample Mendelian randomization analysis

• Published in: Annals of medicine (Helsinki) Vol. 54; no. 1; pp. 1636 - 1645
• Main Authors: Cao, Ziqin, Wu, Yudi, Li, Qiangxiang, Li, Yajia, Wu, Jianhuang
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 31.12.2022; Taylor & Francis Group
• Subjects: Childhood obesity; mendelian randomization; osteoarthritis; Sports Medicine & Musculoskeletal Disorders; osteoarthritis; mendelian randomization; Childhood obesity

It has been found that childhood obesity (CO) may play an important role in the onset and progression of osteoarthritis (OA). Thus we conducted this mendelian randomisation analysis (MR) to evaluate the causal association between childhood obesity and osteoarthritis. Instrumental variables (IVs) wer...