Development of an immune-related prognostic biomarker for triple-negative breast cancer

• Published in: Annals of medicine (Helsinki) Vol. 54; no. 1; pp. 1212 - 1220
• Main Authors: Zhang, Yan, Wang, Quan, Yang, Wei-Kang, Wang, Yong-Si, Zhou, Qiao, Lin, Jie, Wei, Xu-Xuan, Liang, Tian, Liu, Tongtong, Fan, Wen-Tao, Liang, Li, Xu, You-Nian
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 31.12.2022; Taylor & Francis Group
• Subjects: biomarker (BM); Biomarkers; Breast cancer; Clinical Pathology; Cohort Studies; Humans; immunotherapy; microenvironment (ME); Prognosis; prognosis (carcinoma); Triple Negative Breast Neoplasms - diagnosis; Triple Negative Breast Neoplasms - genetics; Tumor Microenvironment; microenvironment (ME); Breast cancer; biomarker (BM); immunotherapy; prognosis (carcinoma)

Purpose: Oncology studies employing digital dissection methodologies have provided some insight on the biological features of tumor microenvironment of Triple-negative breast cancer (TNBC), but molecular diagnostics rarely have therapeutic impact. We aimed to identify a novel prognostic biomarker to...