The Electrophysiologic Effects of Acute Mitral Regurgitation in a Canine Model

• Published in: The Annals of thoracic surgery Vol. 103; no. 4; pp. 1277 - 1284
• Main Authors: Lawrance, Christopher P., MD, Henn, Matthew C., MD, Miller, Jacob R., MD, Kopek, Michael A., MD, Zhang, Andrew J., BA, Schuessler, Richard B., PhD, Damiano, Ralph J., MD
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.04.2017
• Subjects: Acute Disease; Animals; Atrial Fibrillation - diagnosis; Atrial Fibrillation - etiology; Atrial Fibrillation - physiopathology; Atrial Pressure; Cardiothoracic Surgery; Disease Models, Animal; Dogs; Heart Conduction System - physiopathology; Mitral Valve Insufficiency - complications; Mitral Valve Insufficiency - physiopathology; Surgery

Background Atrial fibrillation (AF) occurs in 30% of patients with mitral regurgitation referred for surgical intervention. However, the underlying mechanisms in this population are poorly understood. This study examined the effects of acute left atrial volume overload on atrial electrophysiology an...