Neurological and neuropsychological functions in adults with a history of developmental arsenic poisoning from contaminated milk powder

• Published in: Neurotoxicology and teratology Vol. 53; pp. 75 - 80
• Main Authors: Yorifuji, Takashi, Kato, Tsuguhiko, Ohta, Hitoshi, Bellinger, David C., Matsuoka, Kenichi, Grandjean, Philippe
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.2016
• Subjects: Acoustic Stimulation; Aged; Animals; Arsenic; Arsenic Poisoning - complications; Cognition Disorders - chemically induced; Electroencephalography; Emergency; Evoked Potentials, Auditory - physiology; Female; Food Contamination; Humans; Intelligence Tests; Longitudinal Studies; Male; Medical Education; Middle Aged; Milk; Milk substitute; Nervous System Diseases - chemically induced; Neurologic Examination; Neurological examinations; Neurophysiological monitoring; Neuropsychological Tests; Retrospective Studies; INW, Japan, Honshu, Okayama Prefect; INW, Japan; NCV; VEP; Neurological examinations; Arsenic; BAEP; WAIS-III; Neuropsychological tests; Food contamination; Milk substitute; WRAML2; Neurophysiological monitoring; Wide Range Assessment of Memory and Learning 2; nerve conduction velocity; Wechsler Adults Intelligence Scale III; brainstem auditory evoked potential; visual evoked potential
• ISSN: 0892-0362; 1872-9738; 1872-9738
• DOI: 10.1016/j.ntt.2015.12.001

During the summer of 1955, mass arsenic poisoning of bottle-fed infants occurred in the western part of Japan due to contaminated milk powder, and more than 100 died; some childhood victims were later found to suffer from neurological sequelae in adolescence. This unique incident enabled us to explo...