Non-caloric artificial sweeteners modulate conjugative transfer of multi-drug resistance plasmid in the gut microbiota

• Published in: Gut microbes Vol. 15; no. 1; p. 2157698
• Main Authors: Yu, Zhigang, Henderson, Ian R., Guo, Jianhua
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 31.12.2023; Taylor & Francis Group
• Subjects: 16S rRNA; Animals; Anti-Bacterial Agents - pharmacology; Antibiotic resistance; Bacteria - genetics; conjugation; Drug Resistance, Multiple; Escherichia coli - genetics; Gastrointestinal Microbiome - genetics; gut microbiota; Humans; Mice; non-caloric artificial sweeteners; plasmid; Plasmids - genetics; reactive oxygen species; Research Paper; RNA, Ribosomal, 16S - genetics; Sweetening Agents - pharmacology; 16S rRNA; Antibiotic resistance; reactive oxygen species; plasmid; non-caloric artificial sweeteners; conjugation; gut microbiota

Non-caloric artificial sweeteners have been widely permitted as table sugar substitutes with high intensities of sweetness. They can pass through the intestinal tract without significant metabolization and frequently encounter the gut microbiome, which is composed of diverse bacterial species and is...