Expression pattern, ethanol-metabolizing activities, and cellular localization of alcohol and aldehyde dehydrogenases in human large bowel: association of the functional polymorphisms of ADH and ALDH genes with hemorrhoids and colorectal cancer - Chiang, Chien-Ping; Jao, Shu-Wen; Lee, Shiao-Pieng; Chen, Pei-Chi; Chung, Chia-Chi; Lee, Shou-Lun; Nieh, Shin; Yin, Shih-Jiun (Alcohol (Fayetteville, N.Y.), 2012)
Keywords: Acetaldehyde - metabolism; Activity and cellular localization; Adult; Aged; Aged, 80 and over; Alcohol; Alcohol dehehydrogenase and aldehyde dehydrogenase; Alcohol Dehydrogenase - genetics; Alcohol Dehydrogenase - metabolism; Aldehyde Dehydrogenase - genetics; Aldehyde Dehydrogenase - metabolism; Aldehyde Dehydrogenase, Mitochondrial; Case-Control Studies; Colorectal cancer; Colorectal cancer and hemorrhoid; Colorectal Neoplasms - genetics; Colorectal Neoplasms - metabolism; Ethanol; Ethanol - metabolism; Female; Gene Frequency; Genes; Genetic polymorphism; Genotype; Hemorrhoids - genetics; Hemorrhoids - metabolism; Human rectum and anus; Humans; Immunoblotting; Inactivation, Metabolic; Intestinal Mucosa - enzymology; Isoenzymes - genetics; Isoenzymes - metabolism; Isozyme and allozyme; Male; Metabolism; Metabolites; Middle Aged; Pathogenesis; Polymerase Chain Reaction; Polymorphism, Genetic; Psychiatry; Rectum - enzymology; Studies; Human rectum and anus; Colorectal cancer and hemorrhoid; Isozyme and allozyme; Alcohol dehehydrogenase and aldehyde dehydrogenase; Activity and cellular localization; Genetic polymorphism