LINC00173 facilitates tumor progression by stimulating RAB1B‐mediated PA2G4 and SDF4 secretion in nasopharyngeal carcinoma

• Published in: Molecular oncology Vol. 17; no. 3; pp. 518 - 533
• Main Authors: He, Shi‐Wei, Liang, Ye‐Lin, Zhang, Yuan, Liu, Xu, Gong, Sha, Ye, Ming‐Liang, Huang, Sheng‐Yan, Tan, Xi‐Rong, Zhou, Shi‐Qing, Zhao, Yin, Liu, Na, Li, Ying‐Qing
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.03.2023; John Wiley and Sons Inc; Wiley
• Subjects: Adaptor Proteins, Signal Transducing - metabolism; Antibodies; Biotechnology; Calcium-binding protein; Calcium-Binding Proteins - genetics; Cancer therapies; Cell growth; Cell Line, Tumor; Cell migration; Cell Proliferation; Cloning; Cytoplasm; Gene Expression Regulation, Neoplastic; Glycoproteins - genetics; Humans; LINC00173; Lymph nodes; Mass spectrometry; Medical prognosis; Metastases; Metastasis; mRNA; Nasopharyngeal carcinoma; Nasopharyngeal Carcinoma - genetics; Nasopharyngeal Carcinoma - pathology; Nasopharyngeal Neoplasms - genetics; Nasopharyngeal Neoplasms - pathology; Non-coding RNA; Ontology; PA2G4; Phenotypes; Plasmids; Proteins; rab1 GTP-Binding Proteins - genetics; rab1 GTP-Binding Proteins - metabolism; RAB1B; Reagents; Review boards; RNA, Long Noncoding - genetics; RNA, Long Noncoding - metabolism; RNA-Binding Proteins - metabolism; Scientific imaging; SDF4; Secretion; Therapeutic targets; Tumors; Beijing China; Grand Island New York; United States > US; China; SDF4; nasopharyngeal carcinoma; PA2G4; RAB1B; LINC00173

An increasing number of studies have found that long non‐coding RNA (lncRNA) play important roles in driving the progression of nasopharyngeal carcinoma (NPC). Our microarray screening revealed that expression of the lncRNA long intergenic non‐protein coding RNA 173 (LINC00173) was upregulated in NP...