PHLDA2 is an imprinted gene in cattle

• Published in: Animal genetics Vol. 43; no. 5; pp. 587 - 590
• Main Authors: Sikora, K. M., Magee, D. A., Berkowicz, E. W., Lonergan, P., Evans, A. C. O., Carter, F., Comte, A., Waters, S. M., MacHugh, D. E., Spillane, C.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.10.2012; Wiley Subscription Services, Inc
• Subjects: Animals; bovine; Cattle; Cattle - genetics; Cattle - metabolism; DNA, Complementary - genetics; DNA, Complementary - metabolism; Female; Fetus - metabolism; Genes; Genomic Imprinting; Mammals; Nuclear Proteins - genetics; Nuclear Proteins - metabolism; Offspring; PHLDA2; Placenta; Polymorphism, Single Nucleotide; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger - genetics; RNA, Messenger - metabolism

Summary Genomic imprinting is an epigenetic non‐Mendelian phenomenon found predominantly in placental mammals. Imprinted genes display differential expression in the offspring depending on whether the gene is maternally or paternally inherited. Currently, some 100 imprinted genes have been reported...