Bariatric surgery induces pancreatic cell transdifferentiation as indicated by single‐cell transcriptomics in Zucker diabetic rats - Liang, Yongjun; Widjaja, Jason; Sun, Jiawei; Li, Mengyi; Qiao, Zhengdong; Cao, Ting; Wang, Yueqian; Zhang, Xiong; Zhang, Zhongtao; Gu, Yan; Zhang, Peng; Yang, Jianjun (Journal of diabetes, 2024)
Keywords: Animals; bariatric surgery; Bariatric Surgery - methods; Blood Glucose - metabolism; Cell Transdifferentiation - genetics; Diabetes; Diabetes Mellitus, Experimental - genetics; Diabetes Mellitus, Experimental - metabolism; Diabetes Mellitus, Experimental - surgery; Diabetes Mellitus, Type 2 - genetics; Diabetes Mellitus, Type 2 - metabolism; Diabetes Mellitus, Type 2 - surgery; Gastrointestinal surgery; Glucose; Insulin-Secreting Cells - metabolism; Insulin-Secreting Cells - pathology; Male; Obesity - genetics; Obesity - metabolism; Obesity - surgery; Original; Pancreas - metabolism; Pancreas - pathology; pancreatic cell differentiation; Rats; Rats, Zucker; Single-Cell Analysis - methods; Transcriptome; type 2 diabetes mellitus; type 2 diabetes mellitus; pancreatic cell differentiation; bariatric surgery