Mechanism of neuroprotective action of the anti-Parkinson drug rasagiline and its derivatives - Mandel, Silvia; Weinreb, Orly; Amit, Tamar; Youdim, Moussa B.H. (Brain Research Reviews, 2005)
Keywords: Amyloid beta-Peptides - metabolism; Animals; Anticonvulsants. Antiepileptics. Antiparkinson agents; Apoptosis - drug effects; Bcl-2; Biological and medical sciences; Brain Chemistry - drug effects; Cell death; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Ferritins - metabolism; Humans; Indans - therapeutic use; Ladostigil; MAPK; Medical sciences; Mitochondria - drug effects; Models, Neurological; Monoamine Oxidase Inhibitors - chemistry; Monoamine Oxidase Inhibitors - therapeutic use; Neurology; Neuropharmacology; Neuroprotection; Neuroprotective Agents - therapeutic use; Parkinson Disease - complications; Parkinson Disease - drug therapy; Parkinson's disease; Pharmacology. Drug treatments; PKC; Propargylamine; Protein Kinase C - metabolism; Rasagiline; Signal Transduction - drug effects; Bcl-2; Disorders of the nervous system; Neuroprotection; Parkinson's disease; Propargylamine; Ladostigil; Cell death; Rasagiline; PKC; MAPK; Nervous system diseases; Enzyme; Mitogen-activated protein kinase; Parkinson disease; Review; Antiparkinson agent; Cerebral disorder; Central nervous system disease; Degenerative disease; Mechanism of action; Extrapyramidal syndrome