Iridium-Catalyzed Synthesis of Chiral 1,2,3-Triazoles Units and Precise Construction of Stereocontrolled Oligomers

• Published in: Molecules (Basel, Switzerland) Vol. 28; no. 9; p. 3726
• Main Authors: Zhang, Xueyan, Yu, Tian, Ding, Shengtao
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 26.04.2023; MDPI
• Subjects: Azide; Catalysis; chiral triazole; Circular dichroism; Construction; Cycloaddition; Dichroism; Gases industry; iridium catalysis; Mass spectrometry; Mass spectroscopy; NMR; Nuclear magnetic resonance; Oligomers; optical property; precise construction; Regioselectivity; Size exclusion chromatography; stereoregularity; Triazoles; United States; China; stereoregularity; chiral triazole; optical property; iridium catalysis; precise construction

Iridium-catalyzed azide-thioalkyne cycloaddition reaction (IrAAC) has proved to be a powerful tool for the synthesis of fully substituted 1,2,3-triazole compounds with exclusive regioselectivity. Here we report its successful use in the precise construction of stereocontrolled oligomers that have gr...