Microsatellite marker analysis of Haemonchus contortus populations from Pakistan suggests that frequent benzimidazole drug treatment does not result in a reduction of overall genetic diversity - Chaudhry, Umer; Redman, E. M.; Ashraf, Kamran; Shabbir, Muhammad Zubair; Rashid, Muhammad Imran; Ashraf, Shoaib; Gilleard, John S. (Parasites & vectors, 2016)
Keywords: adults; Animals; Anthelmintics - pharmacology; benzimidazole; Benzimidazoles; Benzimidazoles - pharmacology; Biological diversity; Cloning, Molecular; DNA, Helminth; Dosage and administration; drug therapy; drugs; farms; Forecasts and trends; Gene Expression Regulation - drug effects; Genetic aspects; genetic markers; genetic variation; Genetic Variation - drug effects; geographical distribution; Goat Diseases - drug therapy; Goat Diseases - epidemiology; Goat Diseases - parasitology; Goats; Haemonchus - drug effects; Haemonchus - genetics; Haemonchus contortus; haplotypes; herds; Identification and classification; loci; Microsatellite Repeats; Microsatellites (Genetics); mutation; Pakistan; Pakistan - epidemiology; parasites; Phylogeny; Selection, Genetic; sequence analysis; Sheep; Sheep Diseases - drug therapy; Sheep Diseases - epidemiology; Sheep Diseases - parasitology; small ruminants; tubulin; Tubulin - genetics; Tubulin - metabolism; Pakistan; Haemonchus contortus; Helminth; Albendazole; Anthelmintic; Benzimidazole; Genetic diversity; Drug resistance; Soft selective sweep; β-tubulin