CCL20 is a potential therapeutic target associated with immune infiltration in breast cancer

• Published in: Journal of international medical research Vol. 51; no. 8; p. 3000605231171762
• Main Authors: Zhai, Hongyan, Zhang, Na, Mo, Dan, Qin, Tingting
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.08.2023; Sage Publications Ltd; SAGE Publishing
• Subjects: Biomarkers, Tumor - genetics; Breast cancer; Breast Neoplasms - genetics; Chemokine CCL20 - genetics; Databases, Factual; Female; Humans; Monocytes; Neutrophils; Pre-Clinical Research Report; Prognosis; breast cancer; therapeutic target; interaction network; immune infiltration; biomarker; CCL20

Objectives CCL20 is a chemotactic factor that is involved in immune cell recruitment and cancer progression. However, the role of CCL20 in the prognosis of breast cancer remains unclear. This study analyzed correlations between CCL20 expression and immune infiltration, clinicopathological parameters...