Joint Effects of Environmental Exposures and Familial Susceptibility to Lung Cancer in Chinese Never Smoking Men and Women

• Published in: Journal of thoracic oncology Vol. 9; no. 8; pp. 1066 - 1072
• Main Authors: Tse, Lap Ah, Yu, Ignatius Tak-sun, Rothman, Nathaniel, Ji, Bu-Tian, Qiu, Hong, Wang, Xiao-rong, Hu, Wei, Au, Joseph Siu-kie, Lan, Qing
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.08.2014
• Subjects: Adenocarcinoma - epidemiology; Adenocarcinoma - genetics; Air Pollution, Indoor; Cooking; Diet; Dietary Supplements; Environmental Exposure; Environmental risk factors; Familial susceptibility; Female; Gene-Environment Interaction; Genetic Predisposition to Disease - epidemiology; Hong Kong - epidemiology; Humans; Interaction; Lung neoplasm; Lung Neoplasms - epidemiology; Lung Neoplasms - genetics; Male; Meat; Odds Ratio; Risk Assessment; Risk Factors; Smoke; Vegetables; Vitamins; Hong Kong; Environmental risk factors; Familial susceptibility; Lung neoplasm; Interaction

Previous epidemiological studies had limited power to investigate the joint effects of individual environmental risk factors and familial susceptibility to lung cancer. This study aimed to address this shortcoming. We recruited 345 never smoking lung cancer cases and 828 community referents. We deve...