Utilizing Protein–Peptide Hybrid Microarray for Time-Resolved Diagnosis and Prognosis of COVID-19

• Published in: Microorganisms (Basel) Vol. 11; no. 10; p. 2436
• Main Authors: Zheng, Peiyan, Liao, Baolin, Yang, Jiao, Cheng, Hu, Cheng, Zhangkai J., Huang, Huimin, Luo, Wenting, Sun, Yiyue, Zhu, Qiang, Deng, Yi, Yang, Lan, Zhou, Yuxi, Wu, Wenya, Wu, Shanhui, Cai, Weiping, Li, Yueping, Mo, Xiaoneng, Tan, Xinghua, Li, Linghua, Ma, Hongwei, Sun, Baoqing
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 28.09.2023; MDPI
• Subjects: Antibodies; Biomarkers; blood serum; cost effectiveness; COVID-19; COVID-19 infection; Diagnosis; disease progression; disease severity; Ethics; Hospitals; hybrids; Identification methods; Infections; Medical research; microarray technology; Pandemics; Patients; Peptides; Polypeptides; PPHM assay; Prognosis; Protein arrays; Protein microarrays; Proteins; Quarantine; receptor binding domain (RBD) probe; SARS-CoV-2; sero-IgG dynamic (IsD) events; serological assays; Serology; Severe acute respiratory syndrome coronavirus 2; Viral infections; Viruses; China

The COVID-19 pandemic has highlighted the urgent need for accurate, rapid, and cost-effective diagnostic methods to identify and track the disease. Traditional diagnostic methods, such as PCR and serological assays, have limitations in terms of sensitivity, specificity, and timeliness. To investigat...