Nutrition and the Risk of Alzheimer's Disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that accounts for the major cause of dementia, and the increasing worldwide prevalence of AD is a major public health concern. Increasing epidemiological studies suggest that diet and nutrition might be important modifiable ri...
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Published in | BioMed research international Vol. 2013; no. 2013; pp. 1 - 12 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Cairo, Egypt
Hindawi Publishing Corporation
01.01.2013
John Wiley & Sons, Inc |
Subjects | |
Online Access | Get full text |
ISSN | 2314-6133 2314-6141 2314-6141 |
DOI | 10.1155/2013/524820 |
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Abstract | Alzheimer's disease (AD) is a progressive neurodegenerative disorder that accounts for the major cause of dementia, and the increasing worldwide prevalence of AD is a major public health concern. Increasing epidemiological studies suggest that diet and nutrition might be important modifiable risk factors for AD. Dietary supplementation of antioxidants, B vitamins, polyphenols, and polyunsaturated fatty acids are beneficial to AD, and consumptions of fish, fruits, vegetables, coffee, and light-to-moderate alcohol reduce the risk of AD. However, many of the results from randomized controlled trials are contradictory to that of epidemiological studies. Dietary patterns summarizing an overall diet are gaining momentum in recent years. Adherence to a healthy diet, the Japanese diet, and the Mediterranean diet is associated with a lower risk of AD. This paper will focus on the evidence linking many nutrients, foods, and dietary patterns to AD. |
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AbstractList | Alzheimer's disease (AD) is a progressive neurodegenerative disorder that accounts for the major cause of dementia, and the increasing worldwide prevalence of AD is a major public health concern. Increasing epidemiological studies suggest that diet and nutrition might be important modifiable risk factors for AD. Dietary supplementation of antioxidants, B vitamins, polyphenols, and polyunsaturated fatty acids are beneficial to AD, and consumptions of fish, fruits, vegetables, coffee, and light-to-moderate alcohol reduce the risk of AD. However, many of the results from randomized controlled trials are contradictory to that of epidemiological studies. Dietary patterns summarizing an overall diet are gaining momentum in recent years. Adherence to a healthy diet, the Japanese diet, and the Mediterranean diet is associated with a lower risk of AD. This paper will focus on the evidence linking many nutrients, foods, and dietary patterns to AD. Alzheimer's disease (AD) is a progressive neurodegenerative disorder that accounts for the major cause of dementia, and the increasing worldwide prevalence of AD is a major public health concern. Increasing epidemiological studies suggest that diet and nutrition might be important modifiable risk factors for AD. Dietary supplementation of antioxidants, B vitamins, polyphenols, and polyunsaturated fatty acids are beneficial to AD, and consumptions of fish, fruits, vegetables, coffee, and light-to-moderate alcohol reduce the risk of AD. However, many of the results from randomized controlled trials are contradictory to that of epidemiological studies. Dietary patterns summarizing an overall diet are gaining momentum in recent years. Adherence to a healthy diet, the Japanese diet, and the Mediterranean diet is associated with a lower risk of AD. This paper will focus on the evidence linking many nutrients, foods, and dietary patterns to AD.Alzheimer's disease (AD) is a progressive neurodegenerative disorder that accounts for the major cause of dementia, and the increasing worldwide prevalence of AD is a major public health concern. Increasing epidemiological studies suggest that diet and nutrition might be important modifiable risk factors for AD. Dietary supplementation of antioxidants, B vitamins, polyphenols, and polyunsaturated fatty acids are beneficial to AD, and consumptions of fish, fruits, vegetables, coffee, and light-to-moderate alcohol reduce the risk of AD. However, many of the results from randomized controlled trials are contradictory to that of epidemiological studies. Dietary patterns summarizing an overall diet are gaining momentum in recent years. Adherence to a healthy diet, the Japanese diet, and the Mediterranean diet is associated with a lower risk of AD. This paper will focus on the evidence linking many nutrients, foods, and dietary patterns to AD. |
Audience | Academic |
Author | Hu, Nan Sun, Lei Tan, Lan Tan, Lin Yu, Jin-Tai Wang, Ying-Li |
AuthorAffiliation | 2 College of Medicine and Pharmaceutics, Ocean University of China, Qingdao 266003, China 1 Department of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, Number 5 Donghai Middle Road, Qingdao 266071, China |
AuthorAffiliation_xml | – name: 2 College of Medicine and Pharmaceutics, Ocean University of China, Qingdao 266003, China – name: 1 Department of Neurology, Qingdao Municipal Hospital, School of Medicine, Qingdao University, Number 5 Donghai Middle Road, Qingdao 266071, China |
Author_xml | – sequence: 1 fullname: Sun, Lei – sequence: 2 fullname: Wang, Ying-Li – sequence: 3 fullname: Tan, Lin – sequence: 4 fullname: Yu, Jin-Tai – sequence: 5 fullname: Hu, Nan – sequence: 6 fullname: Tan, Lan |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/23865055$$D View this record in MEDLINE/PubMed |
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References | (29) 2010; 67 (83) 2010; 75 (75) 2011; 30 (159) 2013; 27 (41) 2009; 1281 (62) 2008; 300 (94) 2012; 38 (23) 2001; 30 (16) 2012; 16 (133) 2010; 18 (96) 2010; 9 (54) 2006; 20 (32) 2011; 58 (124) 2003; 41 (3) 2007; 3 (143) 2007; 29 (10) 2002; 13 (21) 2011; 17 (34) 2010; 112 (85) 2012; 7 (33) 2012; 28 (25) 1997; 45 (103) 2011; 59 (141) 2010; 20 (145) 2008; 88 (149) 2010; 21 (44) 2001; 17 (147) 2008; 138 (127) 2007; 11 (22) 2011; 27 (52) 2012; 287 (18) 2012; 28 (114) 2010; 304 (155) 2011; 40 (81) 2013; 33 (74) 2010; 123 (118) 2006; 22 (84) 2011; 37 (67) 2010; 55 (97) 2010; 1 (82) 2010; 74 (24) 1999; 6 (36) 2011 (48) 2010; 13 (53) 2008; 28 (135) 2011; 106 (156) 2010; 25 (104) 2009; 20 (136) 2010; 30 (69) 2009; 66 (60) 2009; 48 (45) 2010; 7 (140) 2010; 20 (148) 2004; 15 (90) 2006; 63 (15) 2002; 18 (27) 2011; 26 (100) 2010; 48 (121) 2007; 4 (158) 2009; 54 (87) 2012; 4 (7) 2007; 42 (46) 2010; 6 (79) 2011; 504 (134) 2006; 67 (123) 2005; 7 (131) 2003; 60 (168) 2010; 92 (150) 2008; 1214 (93) 2008; 115 (42) 2011; 14 (77) 2010; 22 (117) 2010; 9 (31) 2012; 29 (165) 2012; 11 (26) 2002; 451 (129) 2009; 13 (107) 2012; 7 (154) 2009; 17 (138) 2008; 23 (151) 2005; 25 (2) 2010; 19 (5) 2010 (68) 2006; 63 (92) 2012 (13) 2012; 26 (132) 2005; 62 (113) 2009; 5 (99) 2012; 72 (28) 2003; 60 (20) 2012; 12 (153) 2009; 17 (37) 2005; 81 (160) 2008; 46 (58) 2010 (14) 2009; 12 (128) 2007; 69 (38) 2006; 166 (126) 2011; 22 (169) 2004; 363 (55) 2012; 69 (65) 2008; 108 (110) 2009; 33 (73) 2007; 64 (164) 2009; 108 (152) 2012; 16 (98) 2012; 38 (142) 2011; 25 (166) 2004; 363 (6) 2007; 7 (56) 2011; 21 (130) 2005; 65 (111) 2005; 25 (12) 2005; 62 (157) 2011; 6 (40) 2011; 26 (50) 2006; 24 (137) 2001; 115 (162) 2004; 35 (59) 2005; 82 (78); 78 (11) 2009; 66 (125) 2004; 62 (49) 2013; 143 (72) 2005; 1 (144) 2010; 14 (66) 2009; 16 (63) 2013; 97 (43) 2010; 103 (88) 2008; 15 (4) 2012; 31 (47) 2012; 87 (30) 2004; 61 (39) 2008 (57) 2011; 26 (115) 2008; 71 (86) 2011; 94 (120) 2011; 225 (1) 2006; 368 (91) 2011; 24 (9) 2011; 8 (76) 2012; 27 (95) 2010; 19 (146) 2011; 56 (101) 2009; 8, article 25 (112) 2010; 88 (64) 2012; 142 (8) 2013 (105) 2010; 5 (116) 2008; 88 (17) 2008; 22 (71) 2011; 93 (80) 2012; 33 (61) 2011; 19 (89) 2012; 107 (109) 2004; 43 (51) 2009; 16 (170) 2001; 54 (19) 2010; 6 (163) 2007; 28 (70) 2009; 302 (161) 2009; 6 (35) 2000; 2 (119) 2012; 23 (167) 2007; 69 (106) 2012; 3 (122) 1998; 105 (139) 2010; 20 (102) 2003; 51 (108) 2013; 33 88 89 (96) 2010; 5 (90) 2012; 72 (107) 2008; 88 111 112 113 115 116 117 91 92 119 93 94 95 98 11 12 13 15 16 17 18 (110) 2012; 23 120 121 1 122 2 123 3 124 (118) 2007; 11 125 126 6 127 128 8 129 9 20 22 23 26 27 28 29 130 131 132 133 134 135 (99) 2013; 33 137 139 30 31 32 33 34 36 38 140 141 (114) 2005; 7 142 143 144 145 146 147 148 149 40 41 42 43 44 45 46 47 48 151 152 153 (79) 2008; 15 154 156 157 158 159 (155) 2013; 97 50 51 52 53 54 56 57 58 160 161 162 163 164 165 167 168 169 60 61 62 63 64 65 66 67 68 (150) 2013; 27 (78) 2012; 4 170 (72) 2013; 33 70 71 73 74 75 76 77 (136) 2008; 88 (69); 78 (138) 2008; 138 (97) 2012; 3 100 101 102 103 104 105 106 80 81 108 82 109 83 84 85 86 87 |
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SubjectTerms | Alzheimer Disease - complications Alzheimer Disease - physiopathology Alzheimer's disease Diet Dietary supplements Health aspects Humans Malnutrition - complications Malnutrition - physiopathology Nutritional Physiological Phenomena Obesity - complications Obesity - physiopathology Review Risk Factors |
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Title | Nutrition and the Risk of Alzheimer's Disease |
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