Nasal congestion secondary to allergic rhinitis as a cause of sleep disturbance and daytime fatigue and the response to topical nasal corticosteroids

• Published in: Journal of allergy and clinical immunology Vol. 101; no. 5; pp. 633 - 637
• Main Authors: Craig, Timothy J., Teets b, Stephanie, Lehman, Erik B., Chinchilli, Vernon M., Zwillich, Clifford
• Format: Journal Article
• Language: English
• Published: New York, NY Mosby, Inc 01.05.1998; Elsevier
• Subjects: Administration, Topical; Adolescent; Adrenal Cortex Hormones - therapeutic use; Adult; allergic disease; Anti-Allergic Agents - therapeutic use; Biological and medical sciences; corticosteroids; Cross-Over Studies; Double-Blind Method; Ent. Stomatology; fatigue; Fatigue - drug therapy; Fatigue - etiology; Humans; Medical sciences; Middle Aged; nasal congestion; Nasal Obstruction - drug therapy; Pharmacology. Drug treatments; rhinitis; Rhinitis, Allergic, Perennial - drug therapy; Sleep; Sleep Apnea Syndromes - drug therapy; Sleep Apnea Syndromes - etiology; sleep disorders; sleep disturbances; Treatment Outcome; sleep disturbances; AR; fatigue; sleep disorders; Sleep; corticosteroids; nasal congestion; rhinitis; allergic disease; Human; Immunopathology; Allergy; Corticosteroid; Nose disease; Upper respiratory tract; Rhinitis; Treatment efficiency; Antiinflammatory agent; Sleep disorder; Intranasal administration; Obstruction; Prevention; Somnolence; Chemotherapy; Treatment; ENT disease; Complication; Day

Background: Allergic rhinitis (AR) is a frequent disease affecting up to 20% of the population. AR causes a hypersensitivity reaction, which results in inflamed nasal mucosa and nasal congestion. Negative pressure generated during inspiration in the nasal airway secondary to nasal congestion may lea...