Long Noncoding RNA in Prostate, Bladder, and Kidney Cancer

• Published in: European urology Vol. 65; no. 6; pp. 1140 - 1151
• Main Authors: Martens-Uzunova, Elena S., Böttcher, René, Croce, Carlo M., Jenster, Guido, Visakorpi, Tapio, Calin, George A.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier B.V 01.06.2014; Elsevier
• Subjects: Beckwith-Wiedemann syndrome; Biological and medical sciences; Biomarkers, Tumor - genetics; Biomarkers, Tumor - urine; Bladder cancer; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic - genetics; Gynecology. Andrology. Obstetrics; Humans; Kidney cancer; Kidney Neoplasms - diagnosis; Kidney Neoplasms - drug therapy; Kidney Neoplasms - genetics; lncRNA; Long noncoding RNA; Male; Male genital diseases; Medical sciences; Nephrology. Urinary tract diseases; Prostate cancer; Prostatic Neoplasms - diagnosis; Prostatic Neoplasms - drug therapy; Prostatic Neoplasms - genetics; Pseudogenes; Renal cell carcinoma; RNA, Long Noncoding - genetics; RNA, Long Noncoding - urine; RNA, Small Interfering - therapeutic use; Tumors; Tumors of the urinary system; Urinary Bladder Neoplasms - diagnosis; Urinary Bladder Neoplasms - drug therapy; Urinary Bladder Neoplasms - genetics; Urinary tract. Prostate gland; Urology; Urothelial carcinoma; Wilms tumour; Wilms tumour; Beckwith-Wiedemann syndrome; lncRNA; Renal cell carcinoma; Kidney cancer; Long noncoding RNA; Urothelial carcinoma; Bladder cancer; Prostate cancer; Nephrology; Prostate disease; RNA; Non coding sequence; IncRNA; Transitional cell carcinoma; Urology; Wilms tumor; Grawitz tumor; Male genital diseases; Kidney disease; Urinary system disease; Urinary tract disease; Malignant tumor; Congenital disease; Genetic disease; Abdominal disease; Bladder disease; Cancer

Genomic regions without protein-coding potential give rise to millions of protein-noncoding RNA transcripts (noncoding RNA) that participate in virtually all cellular processes. Research over the last 10 yr has accumulated evidence that long noncoding RNAs (lncRNAs) are often altered in human urolog...