Cellular senescence and senescence‐associated secretory phenotype via the cGAS‐STING signaling pathway in cancer - Loo, Tze Mun; Miyata, Kenichi; Tanaka, Yoko; Takahashi, Akiko (Cancer science, 2020)
Keywords: AMP; Cancer; Cancer therapies; Cell cycle; Cell growth; Cell proliferation; Cellular Senescence; cGAS‐STING; Chromatin; Cyclic GMP; Cytokines; Cytoplasm - genetics; Deoxyribonucleic acid; DNA; DNA Damage; Epigenetics; Fibroblasts; Gene expression; Gene Expression Regulation, Neoplastic; Genotype & phenotype; Growth factors; Humans; Immune response; Immunity, Innate; Innate immunity; Interferon; Kinases; Membrane Proteins - metabolism; Mitochondrial DNA; Molecular modelling; Neoplasms - genetics; Neoplasms - metabolism; Nucleotidyltransferases - metabolism; Obesity; Phenotype; Phenotypes; Physiology; Proteins; Review; SASP; Senescence; Signal Transduction; Therapeutic applications; Tumor Microenvironment; Tumor suppression; Tumorigenesis; Tumors; Wound healing; cellular senescence; tumorigenesis; cGAS-STING; SASP; DNA damage