Biologic therapies versus surgical management for aspirin-exacerbated respiratory disease: A review of preliminary data, efficacy, and cost

• Published in: World Journal of Otorhinolaryngology-Head and Neck Surgery Vol. 6; no. 4; pp. 230 - 234
• Main Authors: Workman, Alan D., Bleier, Benjamin S.
• Format: Journal Article
• Language: English
• Published: China Elsevier B.V 01.12.2020; Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA; KeAi Publishing; Wiley
• Subjects: AERD; Biologics; CRSwNP; Dupilumab; Omalizumab; Review; AERD; Omalizumab; CRSwNP; Dupilumab; Biologics

Aspirin-exacerbated respiratory disease (AERD) patients with CRSwNP suffer from reduced quality of life, reduced economic productivity, and higher risk of depression and sleep dysfunction. These patients often require frequent medical and surgical therapy, including functional endoscopic sinus surge...