Parkinson disease polygenic risk score is associated with Parkinson disease status and age at onset but not with alpha-synuclein cerebrospinal fluid levels - Ibanez, Laura; Dube, Umber; Saef, Benjamin; Budde, John; Black, Kathleen; Medvedeva, Alexandra; Del-Aguila, Jorge L.; Davis, Albert A.; Perlmutter, Joel S.; Harari, Oscar; Benitez, Bruno A.; Cruchaga, Carlos (BMC neurology, 2017)
Keywords: Age at onset; Aged; alpha-Synuclein - cerebrospinal fluid; Amyloid beta-Peptides - cerebrospinal fluid; Biomarkers; Biomarkers - cerebrospinal fluid; Development and progression; Female; Genetic aspects; Genetics; Genome-Wide Association Study; Genomics; Humans; Male; Middle Aged; Parkinson disease; Parkinson Disease - physiopathology; Phenotype; Phosphorylation; Polygenic risk score; Risk; Risk factors; tau Proteins - cerebrospinal fluid; Polygenic risk score; Biomarkers; Parkinson disease; Age at onset; Genetics