Surface modification engineering of two-dimensional titanium carbide for efficient synergistic multitherapy of breast cancer

• Published in: Journal of materials chemistry. B, Materials for biology and medicine Vol. 8; no. 3; pp. 642 - 6417
• Main Authors: Bai, Lei, Yi, Wenhui, Sun, Taiyang, Tian, Yilong, Zhang, Ping, Si, Jinhai, Hou, Xun, Hou, Jin
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 05.08.2020
• Subjects: absorption; adsorption; Animals; Antineoplastic Combined Chemotherapy Protocols - chemistry; Antineoplastic Combined Chemotherapy Protocols - pharmacology; Biocompatibility; Biocompatible Materials - chemistry; Breast cancer; breast neoplasms; Breast Neoplasms - drug therapy; Breast Neoplasms - radiotherapy; Chemotherapy; Combined Modality Therapy; Drug delivery; Drug delivery systems; Drug Liberation; drug therapy; Female; Glucans - chemistry; Glucans - pharmacology; Humans; Immune system; Immunomodulation; Immunomodulators; Infrared absorption; Infrared Rays; Lentinan; Lentinan - chemistry; Lentinan - pharmacology; Metastases; Metastasis; Metformin; Metformin - chemistry; Mice, Inbred BALB C; Mice, Nude; mortality; Nanocapsules - chemistry; Nanocomposites; Nanocomposites - chemistry; nanosheets; Nanostructure; Near infrared radiation; Phototherapy; Photothermal conversion; Polysaccharides; Polysaccharides - chemistry; Saccharides; Singlet oxygen; Singlet Oxygen - chemistry; Titanium; Titanium - chemistry; Titanium carbide; Tumors

Cancer is a leading cause of human mortality. Given that it is difficult for conventional therapeutic approaches to effectively eradicate tumors and inhibit their recurrence and metastasis, new therapeutic strategies for solving this problem are urgently needed. In this work, we report the developme...