Grand Research Challenges for Sustainable Industrial Biotechnology

Future manufacturing will focus on new, improved products as well as on new and enhanced production methods. Recent biotechnological and scientific advances, such as CRISPR/Cas and various omic technologies, pave the way to exciting novel biotechnological research, development, and commercialization...

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Bibliographic Details
Published inTrends in biotechnology (Regular ed.) Vol. 37; no. 10; pp. 1042 - 1050
Main Authors Straathof, Adrie J.J, Wahl, S. Aljoscha, Benjamin, Kirsten R, Takors, Ralf, Wierckx, Nick, Noorman, Henk J
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.10.2019
Elsevier Limited
Subjects
Artificial intelligence
Automation
bio-based production
Bioengineering
biological engineering
Biological models (mathematics)
Biomass
bioprocess engineering
Biotechnology
Carbon
Climate change
Commercialization
Consortia
Conversion
CRISPR
Design
Electric power
Electricity distribution
Energy
Engineering
Enzymes
Fermentation
Food
Green products
industrial fermentation
Industrial production
Internal Medicine
Laboratories
Lignin
Mathematical models
Metabolism
Microorganisms
Nanostructured materials
Photovoltaic cells
Production methods
R&D
Raw materials
Research & development
Robustness (mathematics)
Sustainability
Synthesis gas
systems biotechnology
systems biotechnology
bio-based production
biological engineering
bioprocess engineering
industrial fermentation
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Summary:Future manufacturing will focus on new, improved products as well as on new and enhanced production methods. Recent biotechnological and scientific advances, such as CRISPR/Cas and various omic technologies, pave the way to exciting novel biotechnological research, development, and commercialization of new sustainable products. Rigorous mathematical descriptions of microbial cells and consortia thereof will enable deeper biological understanding and lead to powerful in silico cellular models. Biological engineering, namely model-based design together with synthetic biology, will accelerate the construction of robust and high-performing microorganisms. Using these organisms, and ambitions towards zero-concepts with respect to emissions and excess resources in bioprocess engineering, industrial biotechnology is expected to become highly integrated into sustainable generations of technology systems.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0167-7799
1879-3096
DOI:10.1016/j.tibtech.2019.04.002