European Respiratory Society short guidelines for the use of as-needed ICS/formoterol in mild asthma
Recent clinical trials of as-needed fixed-dose combination of inhaled corticosteroid (ICS)/formoterol have provided new evidence that may warrant a reconsideration of current practice. A Task Force was set up by the European Respiratory Society to provide evidence-based recommendations on the use of...
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Published in | The European respiratory journal Vol. 62; no. 4; p. 2300047 |
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Main Authors | , , , , , , , , , , , , , , , |
Format | Journal Article Web Resource |
Language | English |
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England
European Respiratory Society
01.10.2023
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Abstract | Recent clinical trials of as-needed fixed-dose combination of inhaled corticosteroid (ICS)/formoterol have provided new evidence that may warrant a reconsideration of current practice. A Task Force was set up by the European Respiratory Society to provide evidence-based recommendations on the use of as-needed ICS/formoterol as treatment for mild asthma. The Task Force defined two questions that were assessed using the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach. The Task Force utilised the outcomes to develop recommendations for a pragmatic guideline for everyday clinical practice. The Task Force suggests that adults with mild asthma use as-needed ICS/formoterol instead of regular ICS maintenance treatment plus as-needed short-acting β
-antagonist (SABA) and that adolescents with mild asthma use either as-needed ICS/formoterol or ICS maintenance treatment plus as-needed SABA (conditional recommendation; low certainty of evidence). The recommendation for adults places a relatively higher value on the reduction of systemic corticosteroid use and the outcomes related to exacerbations, and a relatively lower value on the small differences in asthma control. Either treatment option is suggested for adolescent patients as the balance is very close and data more limited. The Task Force recommends that adult and adolescent patients with mild asthma use as-needed ICS/formoterol instead of as-needed SABA (strong recommendation; low certainty of evidence). This recommendation is based on the benefit of as-needed ICS/formoterol in mild asthma on several outcomes and the risks related to as-needed SABA in the absence of anti-inflammatory treatment. The implementation of this recommendation is hampered in countries (including European Union countries) where as-needed ICS/formoterol is not approved for mild asthma. |
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AbstractList | Recent clinical trials of as-needed fixed-dose combination of inhaled corticosteroid (ICS)/formoterol have provided new evidence that may warrant a reconsideration of current practice. A Task Force was set up by the European Respiratory Society to provide evidence-based recommendations on the use of as-needed ICS/formoterol as treatment for mild asthma. The Task Force defined two questions that were assessed using the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach. The Task Force utilised the outcomes to develop recommendations for a pragmatic guideline for everyday clinical practice. The Task Force suggests that adults with mild asthma use as-needed ICS/formoterol instead of regular ICS maintenance treatment plus as-needed short-acting β 2 -antagonist (SABA) and that adolescents with mild asthma use either as-needed ICS/formoterol or ICS maintenance treatment plus as-needed SABA (conditional recommendation; low certainty of evidence). The recommendation for adults places a relatively higher value on the reduction of systemic corticosteroid use and the outcomes related to exacerbations, and a relatively lower value on the small differences in asthma control. Either treatment option is suggested for adolescent patients as the balance is very close and data more limited. The Task Force recommends that adult and adolescent patients with mild asthma use as-needed ICS/formoterol instead of as-needed SABA (strong recommendation; low certainty of evidence). This recommendation is based on the benefit of as-needed ICS/formoterol in mild asthma on several outcomes and the risks related to as-needed SABA in the absence of anti-inflammatory treatment. The implementation of this recommendation is hampered in countries (including European Union countries) where as-needed ICS/formoterol is not approved for mild asthma. Recent clinical trials of as-needed fixed-dose combination of inhaled corticosteroid (ICS)/formoterol have provided new evidence that may warrant a reconsideration of current practice. A Task Force was set up by the European Respiratory Society to provide evidence-based recommendations on the use of as-needed ICS/formoterol as treatment for mild asthma. The Task Force defined two questions that were assessed using the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach. The Task Force utilised the outcomes to develop recommendations for a pragmatic guideline for everyday clinical practice. The Task Force suggests that adults with mild asthma use as-needed ICS/formoterol instead of regular ICS maintenance treatment plus as-needed short-acting β -antagonist (SABA) and that adolescents with mild asthma use either as-needed ICS/formoterol or ICS maintenance treatment plus as-needed SABA (conditional recommendation; low certainty of evidence). The recommendation for adults places a relatively higher value on the reduction of systemic corticosteroid use and the outcomes related to exacerbations, and a relatively lower value on the small differences in asthma control. Either treatment option is suggested for adolescent patients as the balance is very close and data more limited. The Task Force recommends that adult and adolescent patients with mild asthma use as-needed ICS/formoterol instead of as-needed SABA (strong recommendation; low certainty of evidence). This recommendation is based on the benefit of as-needed ICS/formoterol in mild asthma on several outcomes and the risks related to as-needed SABA in the absence of anti-inflammatory treatment. The implementation of this recommendation is hampered in countries (including European Union countries) where as-needed ICS/formoterol is not approved for mild asthma. Recent clinical trials of as-needed fixed-dose combination of inhaled corticosteroid (ICS)/formoterol have provided new evidence that may warrant a reconsideration of current practice. A Task Force was set up by the European Respiratory Society to provide evidence-based recommendations on the use of as-needed ICS/formoterol as treatment for mild asthma. The Task Force defined two questions that were assessed using the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach. The Task Force utilised the outcomes to develop recommendations for a pragmatic guideline for everyday clinical practice. The Task Force suggests that adults with mild asthma use as-needed ICS/formoterol instead of regular ICS maintenance treatment plus as-needed short-acting β2-antagonist (SABA) and that adolescents with mild asthma use either as-needed ICS/formoterol or ICS maintenance treatment plus as-needed SABA (conditional recommendation; low certainty of evidence). The recommendation for adults places a relatively higher value on the reduction of systemic corticosteroid use and the outcomes related to exacerbations, and a relatively lower value on the small differences in asthma control. Either treatment option is suggested for adolescent patients as the balance is very close and data more limited. The Task Force recommends that adult and adolescent patients with mild asthma use as-needed ICS/formoterol instead of as-needed SABA (strong recommendation; low certainty of evidence). This recommendation is based on the benefit of as-needed ICS/formoterol in mild asthma on several outcomes and the risks related to as-needed SABA in the absence of anti-inflammatory treatment. The implementation of this recommendation is hampered in countries (including European Union countries) where as-needed ICS/formoterol is not approved for mild asthma. |
Author | Agache, Ioana Peñate Gómez, Deborah Melén, Erik Baraldi, Eugenio Gaga, Mina Tonia, Thomy Papi, Alberto Gotera Rivera, Carolina Maria Schleich, Florence Schuermans, Daniel Beasley, Richard Brusselle, Guy Spanevello, Antonio Coleman, Courtney Pavord, Ian D Ferreira, Diogenes S |
Author_xml | – sequence: 1 givenname: Alberto orcidid: 0000-0002-6924-4500 surname: Papi fullname: Papi, Alberto email: ppa@unife.it organization: A. Papi, D.S. Ferreira and F. Schleich are Task Force co-chairs – sequence: 2 givenname: Diogenes S orcidid: 0000-0002-6086-835X surname: Ferreira fullname: Ferreira, Diogenes S organization: A. Papi, D.S. Ferreira and F. Schleich are Task Force co-chairs – sequence: 3 givenname: Ioana surname: Agache fullname: Agache, Ioana organization: Faculty of Medicine, Transylvania University, Brasov, Romania – sequence: 4 givenname: Eugenio orcidid: 0000-0002-1829-3652 surname: Baraldi fullname: Baraldi, Eugenio organization: Department of Women's and Children's Health, University of Padova, Institute of Pediatric Research "Città della Speranza", Padova, Italy – sequence: 5 givenname: Richard orcidid: 0000-0003-0337-406X surname: Beasley fullname: Beasley, Richard organization: Medical Research Institute of New Zealand, Wellington, New Zealand – sequence: 6 givenname: Guy orcidid: 0000-0001-7021-8505 surname: Brusselle fullname: Brusselle, Guy organization: Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium – sequence: 7 givenname: Courtney orcidid: 0000-0001-7687-1273 surname: Coleman fullname: Coleman, Courtney organization: European Lung Foundation, Sheffield, UK – sequence: 8 givenname: Mina orcidid: 0000-0002-9949-6012 surname: Gaga fullname: Gaga, Mina organization: Athens Chest Hospital, Athens, Greece – sequence: 9 givenname: Carolina Maria surname: Gotera Rivera fullname: Gotera Rivera, Carolina Maria organization: Pulmonology Department, IIS-Fundación Jiménez Díaz, ISCIII, CIBERES, Madrid, Spain – sequence: 10 givenname: Erik orcidid: 0000-0002-8248-0663 surname: Melén fullname: Melén, Erik organization: Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Sachsska Children's Hospital, Stockholm, Sweden – sequence: 11 givenname: Ian D orcidid: 0000-0002-4288-5973 surname: Pavord fullname: Pavord, Ian D organization: Respiratory Medicine Unit and Oxford Respiratory NIHR BRC, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK – sequence: 12 givenname: Deborah surname: Peñate Gómez fullname: Peñate Gómez, Deborah organization: Asthma Patient Representative, London, UK – sequence: 13 givenname: Daniel orcidid: 0000-0002-4877-6778 surname: Schuermans fullname: Schuermans, Daniel organization: Respiratory Division, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium – sequence: 14 givenname: Antonio surname: Spanevello fullname: Spanevello, Antonio organization: Istituti Clinici Scientifici Maugeri IRCCS, Department of Medicine and Cardiopulmonary Rehabilitation, Tradate Institute, Tradate, Italy – sequence: 15 givenname: Thomy surname: Tonia fullname: Tonia, Thomy organization: T. Tonia and F. Schleich contributed equally to this work – sequence: 16 givenname: Florence orcidid: 0000-0002-2678-1373 surname: Schleich fullname: Schleich, Florence organization: A. Papi, D.S. Ferreira and F. Schleich are Task Force co-chairs |
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Cites_doi | 10.1136/thoraxjnl-2017-210650 10.1136/bmjopen-2020-048537 10.1016/j.jclinepi.2010.09.012 10.1016/j.jclinepi.2010.07.015 10.1016/S0140-6736(19)31948-8 10.1111/pai.13885 10.1016/j.jaci.2004.04.042 10.1016/S0140-6736(03)12891-7 10.1002/ppul.25645 10.1056/NEJMoa1715275 10.1186/s13223-021-00610-w 10.1001/jama.2018.2769 10.1186/1471-2466-6-13 10.1016/j.jaci.2020.10.003 10.1056/NEJMoa1715274 10.1016/j.jaip.2021.04.016 10.1016/j.jclinepi.2013.02.003 10.1155/2010/361071 10.1183/23120541.00701-2020 10.1038/s41591-022-01714-5 10.1164/rccm.202109-2205PP 10.1038/npjpcrm.2014.9 10.1136/bmjopen-2012-002247 10.2147/JAA.S176026 10.1056/NEJM200008033430504 10.1183/13993003.01872-2019 10.1164/rccm.202203-0444OC 10.1056/NEJMoa2203163 10.1007/s12325-020-01233-0 10.1001/jamanetworkopen.2022.0615 10.1016/j.jaip.2019.06.030 10.1016/j.rmed.2008.03.020 10.1183/20734735.008914 10.1111/j.1445-5994.1991.tb01385.x 10.1183/16000617.0151-2019 10.1136/bmj.i2016 10.1056/NEJMoa1901963 10.1016/S0140-6736(10)62145-9 10.1136/bmjopen-2016-015245 10.1183/13993003.00606-2022 10.1136/bmjopen-2020-037491 10.1183/13993003.00625-2020 10.1136/thorax-2022-219052 10.1183/23120541.00655-2021 10.1056/NEJMoa063861 10.1016/j.rmed.2020.106079 10.1016/j.jclinepi.2010.04.026 10.1056/NEJMoa2118813 10.1016/j.jaip.2023.01.002 10.1016/j.jaip.2019.03.024 10.1183/09031936.94.07091602 10.1183/13993003.02073-2019 10.1016/S2213-2600(20)30053-9 10.1183/09031936.00075614 10.1164/ajrccm/139.3.806 10.1136/bmj.i2089 10.1001/2012.jama.10893 |
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References | 38575164 - Eur Respir J. 2024 Apr 4;63(4) 38575166 - Eur Respir J. 2024 Apr 4;63(4) Papi (2024102103182776000_62.4.2300047.38) 2022; 386 2024102103182776000_62.4.2300047.29 2024102103182776000_62.4.2300047.25 2024102103182776000_62.4.2300047.26 2024102103182776000_62.4.2300047.27 Kearns (2024102103182776000_62.4.2300047.55) 2022; 78 2024102103182776000_62.4.2300047.28 2024102103182776000_62.4.2300047.21 2024102103182776000_62.4.2300047.65 2024102103182776000_62.4.2300047.22 2024102103182776000_62.4.2300047.23 2024102103182776000_62.4.2300047.24 2024102103182776000_62.4.2300047.62 2024102103182776000_62.4.2300047.63 2024102103182776000_62.4.2300047.20 2024102103182776000_62.4.2300047.64 2024102103182776000_62.4.2300047.60 2024102103182776000_62.4.2300047.5 2024102103182776000_62.4.2300047.6 2024102103182776000_62.4.2300047.7 2024102103182776000_62.4.2300047.8 2024102103182776000_62.4.2300047.9 Wang (2024102103182776000_62.4.2300047.66) 2023; 207 2024102103182776000_62.4.2300047.1 Sumino (2024102103182776000_62.4.2300047.35) 2020; 8 2024102103182776000_62.4.2300047.36 Crossingham (2024102103182776000_62.4.2300047.61) 2021; 5 2024102103182776000_62.4.2300047.2 Beasley (2024102103182776000_62.4.2300047.68) 2020; 133 2024102103182776000_62.4.2300047.3 2024102103182776000_62.4.2300047.4 2024102103182776000_62.4.2300047.39 2024102103182776000_62.4.2300047.34 2024102103182776000_62.4.2300047.30 2024102103182776000_62.4.2300047.31 Tanaka (2024102103182776000_62.4.2300047.33) 2017; 195 Melén (2024102103182776000_62.4.2300047.15) 2022; 33 Israel (2024102103182776000_62.4.2300047.37) 2022; 386 Pavord (2024102103182776000_62.4.2300047.40) 2020; 8 2024102103182776000_62.4.2300047.49 2024102103182776000_62.4.2300047.43 2024102103182776000_62.4.2300047.44 2024102103182776000_62.4.2300047.42 Beasley (2024102103182776000_62.4.2300047.41) 2023; 11 Sadatsafavi (2024102103182776000_62.4.2300047.46) 2021; 17 Price (2024102103182776000_62.4.2300047.53) 2018; 11 Kachroo (2024102103182776000_62.4.2300047.67) 2022; 28 2024102103182776000_62.4.2300047.19 Laba (2024102103182776000_62.4.2300047.58) 2019; 7 2024102103182776000_62.4.2300047.14 2024102103182776000_62.4.2300047.59 2024102103182776000_62.4.2300047.16 Beasley (2024102103182776000_62.4.2300047.48) 1991; 21 2024102103182776000_62.4.2300047.17 Reddel (2024102103182776000_62.4.2300047.32) 2021; 9 2024102103182776000_62.4.2300047.10 2024102103182776000_62.4.2300047.54 2024102103182776000_62.4.2300047.11 FitzGerald (2024102103182776000_62.4.2300047.45) 2020; 171 2024102103182776000_62.4.2300047.12 2024102103182776000_62.4.2300047.56 2024102103182776000_62.4.2300047.13 2024102103182776000_62.4.2300047.57 Pollack (2024102103182776000_62.4.2300047.50) 2022; 28 2024102103182776000_62.4.2300047.51 2024102103182776000_62.4.2300047.52 Beasley (2024102103182776000_62.4.2300047.18) 2022; 5 Buendia (2024102103182776000_62.4.2300047.47) 2021; 56 |
References_xml | – ident: 2024102103182776000_62.4.2300047.5 doi: 10.1136/thoraxjnl-2017-210650 – ident: 2024102103182776000_62.4.2300047.56 doi: 10.1136/bmjopen-2020-048537 – ident: 2024102103182776000_62.4.2300047.24 doi: 10.1016/j.jclinepi.2010.09.012 – ident: 2024102103182776000_62.4.2300047.25 doi: 10.1016/j.jclinepi.2010.07.015 – ident: 2024102103182776000_62.4.2300047.31 doi: 10.1016/S0140-6736(19)31948-8 – volume: 33 start-page: e13885 year: 2022 ident: 2024102103182776000_62.4.2300047.15 article-title: Short-acting β2-agonist use and asthma exacerbations in Swedish children: a SABINA Junior study publication-title: Pediatr Allergy Immunol doi: 10.1111/pai.13885 contributor: fullname: Melén – ident: 2024102103182776000_62.4.2300047.2 doi: 10.1016/j.jaci.2004.04.042 – volume: 195 start-page: A3199 year: 2017 ident: 2024102103182776000_62.4.2300047.33 article-title: Tolerability of as-needed treatment with budesonide and formoterol combination in adult patients with mild asthma publication-title: Am J Respir Crit Care Med contributor: fullname: Tanaka – ident: 2024102103182776000_62.4.2300047.64 doi: 10.1016/S0140-6736(03)12891-7 – volume: 56 start-page: 3699 year: 2021 ident: 2024102103182776000_62.4.2300047.47 article-title: Cost-utility of as-needed combination low-dose budesonide-formoterol in adolescents mild asthma publication-title: Pediatr Pulmonol doi: 10.1002/ppul.25645 contributor: fullname: Buendia – ident: 2024102103182776000_62.4.2300047.29 doi: 10.1056/NEJMoa1715275 – volume: 17 start-page: 108 year: 2021 ident: 2024102103182776000_62.4.2300047.46 article-title: The cost-effectiveness of as-needed budesonide-formoterol versus low-dose inhaled corticosteroid maintenance therapy in patients with mild asthma in Canada publication-title: Allergy Asthma Clin Immunol doi: 10.1186/s13223-021-00610-w contributor: fullname: Sadatsafavi – ident: 2024102103182776000_62.4.2300047.17 doi: 10.1001/jama.2018.2769 – ident: 2024102103182776000_62.4.2300047.11 doi: 10.1186/1471-2466-6-13 – ident: 2024102103182776000_62.4.2300047.44 – ident: 2024102103182776000_62.4.2300047.63 doi: 10.1016/j.jaci.2020.10.003 – volume: 5 start-page: CD013518 year: 2021 ident: 2024102103182776000_62.4.2300047.61 article-title: Combination fixed-dose beta agonist and steroid inhaler as required for adults or children with mild asthma publication-title: Cochrane Database Syst Rev contributor: fullname: Crossingham – ident: 2024102103182776000_62.4.2300047.28 doi: 10.1056/NEJMoa1715274 – volume: 9 start-page: 3069 year: 2021 ident: 2024102103182776000_62.4.2300047.32 article-title: Efficacy and safety of as-needed budesonide-formoterol in adolescents with mild asthma publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2021.04.016 contributor: fullname: Reddel – ident: 2024102103182776000_62.4.2300047.8 – ident: 2024102103182776000_62.4.2300047.51 doi: 10.1016/j.jclinepi.2013.02.003 – volume: 133 start-page: 73 year: 2020 ident: 2024102103182776000_62.4.2300047.68 article-title: Asthma and Respiratory Foundation NZ Adolescent and Adult Asthma Guidelines 2020: a quick reference guide publication-title: NZ Med J contributor: fullname: Beasley – ident: 2024102103182776000_62.4.2300047.3 doi: 10.1155/2010/361071 – ident: 2024102103182776000_62.4.2300047.62 doi: 10.1183/23120541.00701-2020 – volume: 28 start-page: 814 year: 2022 ident: 2024102103182776000_62.4.2300047.67 article-title: Metabolomic profiling reveals extensive adrenal suppression due to inhaled corticosteroid therapy in asthma publication-title: Nat Med doi: 10.1038/s41591-022-01714-5 contributor: fullname: Kachroo – ident: 2024102103182776000_62.4.2300047.19 doi: 10.1164/rccm.202109-2205PP – ident: 2024102103182776000_62.4.2300047.10 doi: 10.1038/npjpcrm.2014.9 – ident: 2024102103182776000_62.4.2300047.42 doi: 10.1136/bmjopen-2012-002247 – ident: 2024102103182776000_62.4.2300047.43 – ident: 2024102103182776000_62.4.2300047.22 – volume: 11 start-page: 193 year: 2018 ident: 2024102103182776000_62.4.2300047.53 article-title: Adverse outcomes from initiation of systemic corticosteroids for asthma: long-term observational study publication-title: J Asthma Allergy doi: 10.2147/JAA.S176026 contributor: fullname: Price – ident: 2024102103182776000_62.4.2300047.49 doi: 10.1056/NEJM200008033430504 – ident: 2024102103182776000_62.4.2300047.1 – ident: 2024102103182776000_62.4.2300047.14 doi: 10.1183/13993003.01872-2019 – volume: 207 start-page: 406 year: 2023 ident: 2024102103182776000_62.4.2300047.66 article-title: Plasticity of individual lung function states from childhood to adulthood publication-title: Am J Respir Crit Care Med doi: 10.1164/rccm.202203-0444OC contributor: fullname: Wang – volume: 386 start-page: 2071 year: 2022 ident: 2024102103182776000_62.4.2300047.38 article-title: Albuterol–budesonide fixed-dose combination rescue inhaler for asthma publication-title: N Engl J Med doi: 10.1056/NEJMoa2203163 contributor: fullname: Papi – ident: 2024102103182776000_62.4.2300047.13 doi: 10.1007/s12325-020-01233-0 – ident: 2024102103182776000_62.4.2300047.59 – volume: 5 start-page: e220615 year: 2022 ident: 2024102103182776000_62.4.2300047.18 article-title: Evaluation of budesonide-formoterol for maintenance and reliever therapy among patients with poorly controlled asthma: a systematic review and meta-analysis publication-title: JAMA Netw Open doi: 10.1001/jamanetworkopen.2022.0615 contributor: fullname: Beasley – volume: 8 start-page: 176 year: 2020 ident: 2024102103182776000_62.4.2300047.35 article-title: A pragmatic trial of symptom-based inhaled corticosteroid use in African-American children with mild asthma publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2019.06.030 contributor: fullname: Sumino – ident: 2024102103182776000_62.4.2300047.6 doi: 10.1016/j.rmed.2008.03.020 – ident: 2024102103182776000_62.4.2300047.7 doi: 10.1183/20734735.008914 – volume: 21 start-page: 753 year: 1991 ident: 2024102103182776000_62.4.2300047.48 article-title: Asthma mortality and inhaled beta agonist therapy publication-title: Aust NZ J Med doi: 10.1111/j.1445-5994.1991.tb01385.x contributor: fullname: Beasley – ident: 2024102103182776000_62.4.2300047.52 doi: 10.1183/16000617.0151-2019 – ident: 2024102103182776000_62.4.2300047.27 doi: 10.1136/bmj.i2016 – ident: 2024102103182776000_62.4.2300047.30 doi: 10.1056/NEJMoa1901963 – ident: 2024102103182776000_62.4.2300047.34 doi: 10.1016/S0140-6736(10)62145-9 – ident: 2024102103182776000_62.4.2300047.60 doi: 10.1136/bmjopen-2016-015245 – ident: 2024102103182776000_62.4.2300047.65 doi: 10.1183/13993003.00606-2022 – ident: 2024102103182776000_62.4.2300047.54 doi: 10.1136/bmjopen-2020-037491 – ident: 2024102103182776000_62.4.2300047.16 doi: 10.1183/13993003.00625-2020 – volume: 78 start-page: 745 year: 2022 ident: 2024102103182776000_62.4.2300047.55 article-title: Single dose of budesonide/formoterol turbuhaler compared to salbutamol pMDI for speed of bronchodilator onset in asthma: a randomised cross-over trial publication-title: Thorax doi: 10.1136/thorax-2022-219052 contributor: fullname: Kearns – ident: 2024102103182776000_62.4.2300047.23 doi: 10.1183/23120541.00655-2021 – ident: 2024102103182776000_62.4.2300047.39 – ident: 2024102103182776000_62.4.2300047.20 doi: 10.1056/NEJMoa063861 – volume: 171 start-page: 106079 year: 2020 ident: 2024102103182776000_62.4.2300047.45 article-title: The cost-effectiveness of as-needed budesonide/formoterol versus low-dose inhaled corticosteroid maintenance therapy in patients with mild asthma in the UK publication-title: Respir Med doi: 10.1016/j.rmed.2020.106079 contributor: fullname: FitzGerald – ident: 2024102103182776000_62.4.2300047.21 doi: 10.1016/j.jclinepi.2010.04.026 – volume: 386 start-page: 1505 year: 2022 ident: 2024102103182776000_62.4.2300047.37 article-title: Reliever-triggered inhaled glucocorticoid in Black and Latinx adults with asthma publication-title: N Engl J Med doi: 10.1056/NEJMoa2118813 contributor: fullname: Israel – volume: 28 start-page: 881 year: 2022 ident: 2024102103182776000_62.4.2300047.50 article-title: The use of short-acting bronchodilators and cost burden of asthma across Global Initiative for Asthma-based severity levels: insights from a large US commercial and managed Medicaid population publication-title: J Manag Care Spec Pharm contributor: fullname: Pollack – volume: 11 start-page: 762 year: 2023 ident: 2024102103182776000_62.4.2300047.41 article-title: The ICS/formoterol reliever therapy regimen in asthma: a review publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2023.01.002 contributor: fullname: Beasley – volume: 7 start-page: 2298 year: 2019 ident: 2024102103182776000_62.4.2300047.58 article-title: Cost-related underuse of medicines for asthma – opportunities for improving adherence publication-title: J Allergy Clin Immunol Pract doi: 10.1016/j.jaip.2019.03.024 contributor: fullname: Laba – ident: 2024102103182776000_62.4.2300047.12 doi: 10.1183/09031936.94.07091602 – ident: 2024102103182776000_62.4.2300047.57 doi: 10.1183/13993003.02073-2019 – volume: 8 start-page: 671 year: 2020 ident: 2024102103182776000_62.4.2300047.40 article-title: Predictive value of blood eosinophils and exhaled nitric oxide in adults with mild asthma: a prespecified subgroup analysis of an open-label, parallel-group, randomised controlled trial publication-title: Lancet Respir Med doi: 10.1016/S2213-2600(20)30053-9 contributor: fullname: Pavord – ident: 2024102103182776000_62.4.2300047.9 doi: 10.1183/09031936.00075614 – ident: 2024102103182776000_62.4.2300047.4 doi: 10.1164/ajrccm/139.3.806 – ident: 2024102103182776000_62.4.2300047.26 doi: 10.1136/bmj.i2089 – ident: 2024102103182776000_62.4.2300047.36 doi: 10.1001/2012.jama.10893 |
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Title | European Respiratory Society short guidelines for the use of as-needed ICS/formoterol in mild asthma |
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