Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort

• Published in: Genetics (Austin) Vol. 200; no. 4; pp. 1051 - 1060
• Main Authors: Kvale, Mark N, Hesselson, Stephanie, Hoffmann, Thomas J, Cao, Yang, Chan, David, Connell, Sheryl, Croen, Lisa A, Dispensa, Brad P, Eshragh, Jasmin, Finn, Andrea, Gollub, Jeremy, Iribarren, Carlos, Jorgenson, Eric, Kushi, Lawrence H, Lao, Richard, Lu, Yontao, Ludwig, Dana, Mathauda, Gurpreet K, McGuire, William B, Mei, Gangwu, Miles, Sunita, Mittman, Michael, Patil, Mohini, Quesenberry, Charles P, Ranatunga, Dilrini, Rowell, Sarah, Sadler, Marianne, Sakoda, Lori C, Shapero, Michael, Shen, Ling, Shenoy, Tanu, Smethurst, David, Somkin, Carol P, Van Den Eeden, Stephen K, Walter, Lawrence, Wan, Eunice, Webster, Teresa, Whitmer, Rachel A, Wong, Simon, Zau, Chia, Zhan, Yiping, Schaefer, Catherine, Kwok, Pui-Yan, Risch, Neil
• Format: Journal Article
• Language: English
• Published: United States Genetics Society of America 01.08.2015
• Subjects: Adult; Aging; Aging - genetics; Body fluids; Cohort Studies; Computational Biology - methods; Deoxyribonucleic acid; DNA; Epidemiology; Female; Genomes; Genotype & phenotype; Genotypes; Genotyping Techniques - methods; Health; Humans; Investigations; Male; Molecular Epidemiology; Oligonucleotide Array Sequence Analysis; Polymorphism, Single Nucleotide; Quality Control; Affymetrix Axiom; genome-wide genotyping; quality control; GERA cohort; saliva DNA

The Kaiser Permanente (KP) Research Program on Genes, Environment and Health (RPGEH), in collaboration with the University of California—San Francisco, undertook genome-wide genotyping of >100,000 subjects that constitute the Genetic Epidemiology Research on Adult Health and Aging (GERA) cohort....