Migratory properties of cultured olfactory ensheathing cells by single-cell migration assay

• Published in: Cell research Vol. 18; no. 4; pp. 479 - 490
• Main Authors: Huang, Zhi-hui, Wang, Ying, Cao, Li, Su, Zhi-da, Zhu, Yan-ling, Chen, Yi-zhang, Yuan, Xiao-bing, He, Cheng
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.04.2008; Nature Publishing Group
• Subjects: Animals; Biological Assay - methods; Biomedical and Life Sciences; Cell Biology; Cell Line, Transformed; Cell Movement - drug effects; Cells, Cultured; Cytoskeleton - drug effects; Injuries; Laminin - metabolism; Life Sciences; Lysophospholipids - pharmacology; Male; Olfactory Bulb - cytology; Olfactory Bulb - drug effects; original-article; Rats; Rats, Sprague-Dawley; Schwann Cells - cytology; Schwann Cells - drug effects; Subpopulations; 嗅觉细胞; 形态学; 神经细胞; 细胞移植; motility; single-cell migration; olfactory ensheathing cells; morphology; LPA

Olfactory ensheathing cells （OECs） are a unique type of glial cells that have axonal growth-promoting properties. OEC transplantation has emerged as a promising experimental therapy of axonal injuries and demyelinating diseases. However, some fundamental cellular properties of OECs remain unclear. I...