Serum CCL20 combined with IL-17A as early diagnostic and prognostic biomarkers for human colorectal cancer

• Published in: Journal of translational medicine Vol. 17; no. 1; pp. 253 - 11
• Main Authors: Wang, Dan, Yuan, Weitang, Wang, Yaping, Wu, Qian, Yang, Li, Li, Feng, Chen, Xinfeng, Zhang, Zhen, Yu, Weina, Maimela, Nomathamsanqa Resegofetse, Cao, Ling, Wang, Dong, Wang, Junxia, Sun, Zhenqiang, Liu, Jinbo, Zhang, Yi
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 06.08.2019; BioMed Central; BMC
• Subjects: Adenoma; Antigens; Biological markers; Cancer diagnosis; Cancer screening; Carcinoembryonic antigen; CCL20; Chemokines; Colitis; Colorectal cancer; Computational biology; Diagnosis; Genetic aspects; Genetic markers; Genetic research; Health aspects; Identification and classification; IL-17A; Immunohistochemistry; Inflammation; Interleukin-17; Novels; Patient outcomes; Prognosis; Tumors; China; Prognosis; Diagnosis; IL-17A; CCL20; Colorectal cancer

Noninvasive and effective methods of early diagnosis of colorectal cancer (CRC) are underexplored. Inflammation is known to play an important role in the tumor microenvironment of CRC. Therefore, the aim of this study was to elucidate novel inflammatory biomarkers related to early diagnosis and prog...