Relative efficacy of catheter ablation vs antiarrhythmic drugs in treating premature ventricular contractions: A single-center retrospective study

• Published in: Heart rhythm Vol. 11; no. 2; pp. 187 - 193
• Main Authors: Zhong, Li, Lee, Ying-Hsiang, Huang, Xin-Miao, Asirvatham, Samuel J., Shen, Win-Kuang, Friedman, Paul A., Hodge, David O., Slusser, Joshua P., Song, Zhi-Yuan, Packer, Douglas L., Cha, Yong-Mei
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2014
• Subjects: Anti-Arrhythmia Agents - therapeutic use; Antiarrhythmic drug; Cardiovascular; Catheter Ablation; Echocardiography; Electrocardiography; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Humans; Left ventricular dysfunction; Male; Middle Aged; Multivariate Analysis; Premature ventricular contraction; Premature ventricular contraction–induced cardiomyopathy; Radiofrequency catheter ablation; Stroke Volume; Treatment Outcome; Ventricular Premature Complexes - physiopathology; Ventricular Premature Complexes - therapy; CCB; AAD; RV; CAD; NSVT; ECG; LVEF; Left ventricular dysfunction; Premature ventricular contraction; LV; LVEDD; LVOT; RFA; PVC-CMP; DCM; RVOT; Radiofrequency catheter ablation; ICM; Premature ventricular contraction–induced cardiomyopathy; LVESD; Antiarrhythmic drug; PVC; coronary artery disease; premature ventricular contraction; left ventricular/ventricle; antiarrhythmic drug; left ventricular end-diastolic dimension; left ventricular ejection fraction; right ventricular outflow tract; electrocardiogram; dilated cardiomyopathy; right ventricular/ventricle; left ventricular end-systolic dimension; left ventricular outflow tract; premature ventricular contraction–induced cardiomyopathy; ischemic cardiomyopathy; nonsustained ventricular tachycardia; calcium channel blocker; radiofrequency ablation

It is unknown whether radiofrequency ablation (RFA) or antiarrhythmic therapy is superior when treating patients with symptomatic premature ventricular contractions (PVCs). To determine the relative efficacy of RFA and antiarrhythmic drugs (AADs) on PVC burden reduction and increasing left ventricul...