Detection of IgA Antiphospholipid Antibodies Does not Improve Thrombotic Antiphospholipid Syndrome Classification: A two-Center Study

• Published in: Clinical and applied thrombosis/hemostasis Vol. 28; p. 10760296221081129
• Main Authors: Su, Zhenzhen, Huang, Zhuochun, Zhao, Jiuliang, Li, Mengtao, Hu, Jing, Zeng, Xiaofeng, Hu, Chaojun, Yang, Bin
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.04.2022; SAGE PUBLICATIONS, INC; SAGE Publishing
• Subjects: Antibodies; Antibodies, Antiphospholipid; Antiphospholipid Syndrome - diagnosis; Autoimmune diseases; beta 2-Glycoprotein I; Classification; Humans; Immunoglobulin A; Laboratories; Original Manuscript; Thrombosis; thrombotic antiphospholipid syndrome, anti-β2 glycoprotein I antibody, anticardiolipin antibody, immunoglobulin A, classification

Background Thrombotic antiphospholipid syndrome (APS) is a systemic autoimmune disease; its diagnosis requires meeting both clinical and laboratory criteria. Prevalence rates of immunoglobulin (Ig) A anticardiolipin antibodies (aCL) and IgA anti-β2 glycoprotein I antibodies (aβ2GPI) remain unknown,...