Contact pathway of coagulation and inflammation

• Published in: Thrombosis journal Vol. 13; no. 1; p. 17
• Main Author: Wu, Yi
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 06.05.2015; BioMed Central
• Subjects: Analysis; Bradykinin; Inflammation; Kallikrein; Physiological aspects; Review; Infection; Platelet; Coagulation; Contact system; Autoimmune disease; Inflammation; Vascular biology

The contact system, also named as plasma kallikrein-kinin system, consists of three serine proteinases: coagulation factors XII (FXII) and XI (FXI), and plasma prekallikrein (PK), and the nonenzymatic cofactor high molecular weight kininogen (HK). This system has been investigated actively for more...