Simple bioconjugate chemistry serves great clinical advances: albumin as a versatile platform for diagnosis and precision therapy

• Published in: Chemical Society reviews Vol. 45; no. 5; pp. 1432 - 1456
• Main Authors: Liu, Zhibo, Chen, Xiaoyuan
• Format: Journal Article
• Language: English
• Published: England 07.03.2016
• Subjects: Albumins; Bright plating; chemistry; Coupling (molecular); Diagnosis; Drug Delivery Systems; Drugs; encapsulation; human serum albumin; Humans; nanoparticles; Peptides; Pharmaceutical Preparations - chemistry; pharmacokinetics; Platforms; Proteins; Serum Albumin - chemistry; therapeutics

Albumin is the most abundant circulating protein in plasma and has recently emerged as a versatile protein carrier for drug targeting and for improving the pharmacokinetic profile of peptide or protein based drugs. Three drug delivery technologies related to albumin have been developed, which includ...