Head Injury and Amyotrophic Lateral Sclerosis

• Published in: American journal of epidemiology Vol. 166; no. 7; pp. 810 - 816
• Main Authors: Chen, Honglei, Richard, Marie, Sandler, Dale P., Umbach, David M., Kamel, Freya
• Format: Journal Article
• Language: English
• Published: Cary, NC Oxford University Press 01.10.2007; Oxford Publishing Limited (England)
• Subjects: Adult; Adult and adolescent clinical studies; Aged; Aged, 80 and over; Amyotrophic lateral sclerosis; Amyotrophic Lateral Sclerosis - epidemiology; Amyotrophic Lateral Sclerosis - etiology; Analysis. Health state; Athletes; Biological and medical sciences; Case-Control Studies; closed; Confidence Intervals; craniocerebral trauma; Craniocerebral Trauma - complications; Craniocerebral Trauma - epidemiology; Epidemiology; Female; General aspects; Head injuries; Humans; Injuries of the nervous system and the skull. Diseases due to physical agents; Life Style; Male; Medical sciences; Meta-analysis; Middle Aged; New England - epidemiology; Odds Ratio; Organic mental disorders. Neuropsychology; penetrating; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Public health. Hygiene; Public health. Hygiene-occupational medicine; Risk Assessment; Risk Factors; Soccer - injuries; Traumas. Diseases due to physical agents; New England; craniocerebral trauma; amyotrophic lateral sclerosis; head injuries, closed; head injuries, penetrating; Human; Nervous system diseases; closed; head injuries; Craniocerebral; Amyotrophic lateral sclerosis; penetrating; Epidemiology; Central nervous system disease; Degenerative disease; Head trauma; Spinal cord disease; Public health; amyotrophic lateral sclerosis; craniocerebral trauma; head injuries

Recent data showed that soccer players in Italy had an unusually high risk of amyotrophic lateral sclerosis (ALS) and that repeated head trauma might have contributed to this increase. The authors examined whether head injury was related to ALS risk in a case-control study of 109 New England ALS cas...