Vascular function assessed by passive leg movement and flow-mediated dilation: initial evidence of construct validity

• Published in: American journal of physiology. Heart and circulatory physiology Vol. 311; no. 5; pp. H1277 - H1286
• Main Authors: Rossman, Matthew J., Groot, H. Jonathan, Garten, Ryan S., Witman, Melissa A. H., Richardson, Russell S.
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.11.2016
• Subjects: Age Factors; Aged; Brachial Artery - physiology; Correlation analysis; Endothelium, Vascular - physiology; Femoral Artery - physiology; Humans; Integrative Cardiovascular Physiology and Pathophysiology; Leg - blood supply; Legs; Male; Movement; Movement - physiology; Nitric Oxide; Posture; Regional Blood Flow - physiology; Reproducibility of Results; Retrospective Studies; Supine Position; Vasodilation - physiology; Veins & arteries; Young Adult; cardiovascular disease; endothelium; nitric oxide; aging

The vasodilatory response to passive leg movement (PLM) appears to provide a novel, noninvasive assessment of vascular function. However, PLM has yet to be compared with the established noninvasive assessment of vascular health, flow-mediated dilation (FMD). Therefore, as an initial evaluation of th...