Glucose-6-phosphate dehydrogenase activity measured by spectrophotometry and associated genetic variants from the Oromiya zone, Ethiopia

• Published in: Malaria journal Vol. 17; no. 1; pp. 358 - 10
• Main Authors: Kießling, Nora, Brintrup, Joaquin, Zeynudin, Ahmed, Abduselam, Nuredin, Götz, Sylvia, Mack, Margith, Pritsch, Michael, Wieser, Andreas, Kohne, Elisabeth, Berens-Riha, Nicole
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 12.10.2018; BioMed Central; BMC
• Subjects: Adult; Antimalarials - therapeutic use; Care and treatment; Development and progression; Ethiopia; Female; Genetic aspects; Genetic Variation; Glucose-6-phosphate dehydrogenase deficiency; Glucosephosphate Dehydrogenase - genetics; Glucosephosphate Dehydrogenase Deficiency - epidemiology; Glucosephosphate Dehydrogenase Deficiency - genetics; Health aspects; Humans; Male; Primaquine - therapeutic use; Quinolines; Spectrophotometry; Young Adult; Ethiopia

The study aimed to gain first data on the prevalence of G6PD enzyme deficiency measured by spectrophotometry and associated genetic variants in Jimma and surroundings, Ethiopia. The area is a Plasmodium vivax endemic region, but 8-aminoquinolines such as primaquine are not recommended as G6PD testin...