Inflammation in multiple sclerosis

• Published in: Therapeutic advances in neurological disorders Vol. 14; p. 17562864211007687
• Main Authors: Haase, Stefanie, Linker, Ralf A.
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 2021; SAGE PUBLICATIONS, INC; SAGE Publishing
• Subjects: Antigens; Autoantigens; Autoimmune Neurology; Central nervous system; Demyelination; Gliosis; Inflammation; Inflammatory diseases; Lymphocytes B; Lymphocytes T; Macrophages; Multiple sclerosis; Myeloid cells; Pathology; Phenotypes; myeloid cells; inflammation; B cells; T cells; immune network; immune regulation; relapsing-remitting multiple sclerosis

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) that is characterised pathologically by demyelination, gliosis, neuro-axonal damage and inflammation. Despite intense research, the underlying pathomechanisms driving inflammatory demyelination in MS still...