Telocytes Enhances M1 Differentiation and Phagocytosis While Inhibits Mitochondria-Mediated Apoptosis Via Activation of NF-κB in Macrophages

• Published in: Cell transplantation Vol. 30; p. 9636897211002762
• Main Authors: Huang, Yue-Lin, Zhang, Fei-Lei, Tang, Xue-Ling, Yang, Xiao-Jun
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 2021; Sage Publications Ltd; SAGE Publishing
• Subjects: Apoptosis; Bcl-2 protein; Bcl-x protein; CD34 antigen; Cell activation; Cell culture; Cell differentiation; Dexamethasone; Endometriosis; Endometrium; Energy metabolism; Gynecological diseases; Macrophages; Membrane potential; Metabolism; Mitochondria; NF-κB protein; Original; Peritoneum; Phagocytosis; Phenotypes; Vimentin; mitochondria-mediated apoptosis; endometriosis; NF-κB; M1 macrophages; bax/bcl-caspase9-caspase3 signaling pathway; telocytes

Telocytes (TCs), which are a recently discovered interstitial cell type present in various organs and tissues, perform multiple biological functions and participate in extensive crosstalk with neighboring cells. Endometriosis (EMs) is a gynecological disease characterized by the presence of viable e...