Progesterone Enhances the Invasion of Trophoblast Cells by Activating PI3K/AKT Signaling Pathway to Prevent Preeclampsia - Liu, Hongyu; Yu, Ling; Ding, Yiling; Peng, Mei; Deng, Yali (Cell transplantation, 2023)
Keywords: 1-Phosphatidylinositol 3-kinase; AKT protein; Animals; Arteriosclerosis; Blood levels; Blood pressure; Cell Movement; Cell proliferation; Cell viability; Cholecystokinin; Cyclin D1; Cyclin D1 - metabolism; Enzyme-linked immunosorbent assay; Female; Gelatinase A; Gelatinase B; Humans; IL-1β; Inflammation; Interleukin 10; Interleukin 13; Interleukin 4; Interleukin-10 - metabolism; Interleukin-13 - metabolism; Interleukin-4 - metabolism; Matrix Metalloproteinase 2 - metabolism; Matrix Metalloproteinase 9 - metabolism; Original; Phosphatidylinositol 3-Kinases - metabolism; Placenta - metabolism; Pre-eclampsia; Pre-Eclampsia - metabolism; Preeclampsia; Pregnancy; Progesterone; Progesterone - pharmacology; Proliferating cell nuclear antigen; Proliferating Cell Nuclear Antigen - metabolism; Proto-Oncogene Proteins c-akt - metabolism; Rats; Signal transduction; Signal Transduction - physiology; Trophoblasts - metabolism; Tumor Necrosis Factor-alpha - metabolism; Tumor necrosis factor-α; Uterus; HTR-8/SVneo; preeclampsia; PI3K/AKT signaling pathway; progesterone