Diagnostic values of MMP-7, MMP-9, MMP-11, TIMP-1, TIMP-2, CEA, and CA19-9 in patients with colorectal cancer

• Published in: Journal of international medical research Vol. 49; no. 5; p. 3000605211012570
• Main Authors: Huang, Xiwen, Lan, Yongquan, Li, En, Li, Jiaquan, Deng, Qiaoting, Deng, Xunwei
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.05.2021; Sage Publications Ltd; SAGE Publishing
• Subjects: Antigens; Biomarkers; Biomarkers, Tumor; CA-19-9 Antigen; Carcinoembryonic Antigen; Colorectal cancer; Colorectal Neoplasms - diagnosis; Humans; Matrix Metalloproteinase 11; Matrix Metalloproteinase 7; Matrix Metalloproteinase 9; Prognosis; Retrospective Clinical Research Report; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; carcinoembryonic antigen; Colorectal cancer; matrix metalloproteinase-7; combined detection; tissue inhibitor of metalloproteinase-1; diagnosis; biomarker

Objective Colorectal cancer (CRC) is one of the most common and lethal malignancies. The identification of precise and noninvasive biomarkers is urgently needed to aid the early diagnosis and clinical management of CRC. Methods A total of 112 patients with CRC and 115 healthy control subjects were i...