Long-term disability trajectories in relapsing multiple sclerosis patients treated with early intensive or escalation treatment strategies

• Published in: Therapeutic advances in neurological disorders Vol. 14; p. 17562864211019574
• Main Authors: Iaffaldano, Pietro, Lucisano, Giuseppe, Caputo, Francesca, Paolicelli, Damiano, Patti, Francesco, Zaffaroni, Mauro, Brescia Morra, Vincenzo, Pozzilli, Carlo, De Luca, Giovanna, Inglese, Matilde, Salemi, Giuseppe, Maniscalco, Giorgia Teresa, Cocco, Eleonora, Sola, Patrizia, Lus, Giacomo, Conte, Antonella, Amato, Maria Pia, Granella, Franco, Gasperini, Claudio, Bellantonio, Paolo, Totaro, Rocco, Rovaris, Marco, Salvetti, Marco, Torri Clerici, Valentina Liliana Adriana, Bergamaschi, Roberto, Maimone, Davide, Scarpini, Elio, Capobianco, Marco, Comi, Giancarlo, Filippi, Massimo, Trojano, Maria
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 2021; SAGE PUBLICATIONS, INC; SAGE Publishing
• Subjects: Azathioprine; Cladribine; Copolymer 1; Interferon; Mitoxantrone; Monoclonal antibodies; Multiple sclerosis; Original Research; Patients; disability trajectories; big data; disease registry; multiple sclerosis

Background and aims: No consensus exists on how aggressively to treat relapsing–remitting multiple sclerosis (RRMS) nor on the timing of the treatment. The objective of this study was to evaluate disability trajectories in RRMS patients treated with an early intensive treatment (EIT) or with a moder...