Evaluation of Proposed In Vivo Probe Substrates and Inhibitors for Phenotyping Transporter Activity in Humans - Momper, Jeremiah D; Tsunoda, Shirley M; Ma, Joseph D (Journal of clinical pharmacology, 2016)
Keywords: Animals; ATP-Binding Cassette Transporters; Biological Transport - drug effects; Biological Transport - physiology; Decision Trees; Drug Evaluation, Preclinical - methods; Drug Interactions - physiology; Humans; Membrane Transport Modulators - metabolism; Membrane Transport Modulators - pharmacology; Membrane Transport Proteins - metabolism; Organic Anion Transporters - metabolism; Organic Cation Transport Proteins - metabolism; Pharmaceutical Preparations - administration & dosage; Pharmaceutical Preparations - metabolism; Phenotype; Substrate Specificity - physiology; drug development; biomarker; drug-drug interaction; phenotyping; transporter