In Medication-Overuse Headache, fMRI Shows Long-Lasting Dysfunction in Midbrain Areas - Ferraro, Stefania; Grazzi, Licia; Muffatti, Riccardo; Nava, Simone; Ghielmetti, Francesco; Bertolino, Nicola; Mandelli, Maria Luisa; Visintin, Eleonora; Bruzzone, Maria Grazia; Nigri, Anna; Epifani, Francesca; Bussone, Gennaro; et al. (Headache, 2012)
Keywords: Addiction; Addictions; Addictive behaviors; Adult; Biological and medical sciences; Brain; Circuits; Cortex (prefrontal); Data processing; Decision making; decision-making under risk; Dopamine; Female; Functional magnetic resonance imaging; Headache; Headache Disorders, Secondary - diagnosis; Headache Disorders, Secondary - physiopathology; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy; Headaches; Humans; Magnetic Resonance Imaging - trends; Medical sciences; medication-overuse headache; Mesencephalon; Mesencephalon - physiopathology; mesocorticolimbic dopamine circuit; Middle Aged; Migraine; Nervous system (semeiology, syndromes); Neuroimaging; Neurology; NMR; Nuclear magnetic resonance; Substantia nigra; Time Factors; Vascular diseases and vascular malformations of the nervous system; Ventral tegmentum; Withdrawal; Headache; Nervous system diseases; Dopamine; Decision making; medication-overuse headache; Midbrain; Catecholamine; Nuclear magnetic resonance imaging; Cerebral disorder; mesocorticolimbic dopamine circuit; Chemotherapy; Treatment; Pain; Addiction; Central nervous system disease; Risk factor; Neurotransmitter; Drug of abuse; decision-making under risk; Neurological disorder; Long lasting; Cerebrovascular disease; functional magnetic resonance imaging; Functional imaging; addiction