Branching Morphogenesis

• Published in: Circulation research Vol. 103; no. 8; pp. 784 - 795
• Main Authors: Horowitz, Arie, Simons, Michael
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD American Heart Association, Inc 10.10.2008; Lippincott
• Subjects: Animals; Biological and medical sciences; Blood Vessels - embryology; Blood Vessels - metabolism; Body Patterning; Cell Differentiation; Cell Proliferation; Drosophila melanogaster; Fundamental and applied biological sciences. Psychology; Humans; Intracellular Signaling Peptides and Proteins - metabolism; Lung - embryology; Lung - metabolism; Mice; Morphogenesis; Neovascularization, Physiologic; Retinal Vessels - embryology; Signal Transduction; Trachea - embryology; Trachea - metabolism; Ureter - embryology; Ureter - metabolism; Vertebrates: cardiovascular system; Zebrafish; Respiratory tract; Morphogenesis; Branching; Vertebrata; Mammalia; tubulogenesis; ureteric system; vascular system; Circulatory system; tracheal system; Respiratory system; Trachea

Tubular structures are a fundamental anatomic theme recurring in a wide range of animal species. In mammals, tubulogenesis underscores the development of several systems and organs, including the vascular system, the lungs, and the kidneys. All tubular systems are hierarchical, branching into segmen...