Clinical and Molecular Features of Hürthle Cell Carcinoma of the Thyroid

• Published in: The journal of clinical endocrinology and metabolism Vol. 100; no. 1; pp. 55 - 62
• Main Authors: Chindris, Ana-Maria, Casler, John D., Bernet, Victor J., Rivera, Michael, Thomas, Colleen, Kachergus, Jennifer M., Necela, Brian M., Hay, Ian D., Westphal, Sydney A., Grant, Clive S., Thompson, Geoffrey B., Schlinkert, Richard T., Thompson, E. Aubrey, Smallridge, Robert C.
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.01.2015; Copyright by The Endocrine Society
• Subjects: Adenocarcinoma, Follicular - genetics; Adenocarcinoma, Follicular - metabolism; Adenocarcinoma, Follicular - pathology; Adolescent; Adult; Aged; Aged, 80 and over; Computed tomography; Death; Female; Females; Follow-Up Studies; Humans; Invasiveness; Iodine; Male; Males; Metastases; Metastasis; Middle Aged; mRNA; Mutation; Neoplasm Recurrence, Local - genetics; Neoplasm Recurrence, Local - metabolism; Neoplasm Recurrence, Local - pathology; Patients; Prognosis; Promoter Regions, Genetic; Retrospective Studies; Sex Factors; Telomerase - genetics; Telomerase - metabolism; Thyroglobulin; Thyroid; Thyroid cancer; Thyroid carcinoma; Thyroid gland; Thyroid Neoplasms - genetics; Thyroid Neoplasms - metabolism; Thyroid Neoplasms - pathology; Young Adult

Context:Hürthle cell cancer (HCC) of the thyroid remains the subject of controversy with respect to natural course, treatment, and follow-up.Objective:The objective of the study was to evaluate the clinical and molecular features associated with outcome in HCC.Design:The study was a review of 173 HC...