Collagen fibrils in functionally distinct tendons have differing structural responses to tendon rupture and fatigue loading

• Published in: Acta biomaterialia Vol. 42; pp. 296 - 307
• Main Authors: Herod, Tyler W., Chambers, Neil C., Veres, Samuel P.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 15.09.2016
• Subjects: Animals; Assessments; Biomechanical Phenomena; Calorimetry, Differential Scanning; Cattle; Collagen fibril; Collagens; Crosslinking; Damage; Fatigue failure; Fatigue strength; Fibrillar Collagens - chemistry; Fibrillar Collagens - metabolism; Fibrillar Collagens - ultrastructure; Flexors; Isometric Contraction; Mechanics; Muscle Fatigue; Rupture; Scanning electron microscopy; Structure-function; Temperature; Tendon; Tendons; Tendons - pathology; Tendons - physiopathology; Tendons - ultrastructure; Weight-Bearing; Mechanics; Collagen fibril; Damage; Structure-function; Tendon

[Display omitted] In this study we investigate relationships between the nanoscale structure of collagen fibrils and the macroscale functional response of collagenous tissues. To do so, we study two functionally distinct classes of tendons, positional tendons and energy storing tendons, using a bovi...